Mobile genetic elements associated with antimicrobial resistance

SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …

Transfer of antibiotic resistance in Staphylococcus aureus

J Haaber, JR Penadés, H Ingmer - Trends in microbiology, 2017 - cell.com
Staphylococcus aureus is a serious human pathogen with remarkable adaptive powers.
Antibiotic-resistant clones rapidly emerge mainly by acquisition of antibiotic-resistance …

Bacterial chromosomal mobility via lateral transduction exceeds that of classical mobile genetic elements

S Humphrey, A Fillol-Salom, N Quiles-Puchalt… - Nature …, 2021 - nature.com
It is commonly assumed that the horizontal transfer of most bacterial chromosomal genes is
limited, in contrast to the frequent transfer observed for typical mobile genetic elements …

Diverse mobilization strategies facilitate transfer of non-conjugative mobile genetic elements

JP Ramsay, N Firth - Current opinion in microbiology, 2017 - Elsevier
Highlights•Non-conjugative mobile genetic elements are often mobilized by conjugative
elements.•Element carriage of a relaxase gene is not a strict requirement for mobilization.•A …

[HTML][HTML] Underrated Staphylococcus species and their role in antimicrobial resistance spreading

CC Rossi, MF Pereira… - Genetics and molecular …, 2020 - SciELO Brasil
The increasing threat of antimicrobial resistance has shed light on the interconnection
between humans, animals, the environment, and their roles in the exchange and spreading …

[HTML][HTML] Interactions between plasmids and other mobile genetic elements affect their transmission and persistence

F Dionisio, R Zilhão, JA Gama - Plasmid, 2019 - Elsevier
Plasmids are genetic elements that play a role in bacterial evolution by providing new genes
that promote adaptation to diverse conditions. Plasmids are also known to reduce bacterial …

Structure and Evolution of Acinetobacter baumannii Plasmids

AD Salgado-Camargo, S Castro-Jaimes… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii is an emergent bacterial pathogen that provokes many types of
infections in hospitals around the world. The genome of this organism consists of a …

An updated view of plasmid conjugation and mobilization in Staphylococcus

JP Ramsay, SM Kwong, RJT Murphy… - Mobile genetic …, 2016 - Taylor & Francis
The horizontal gene transfer facilitated by mobile genetic elements impacts almost all areas
of bacterial evolution, including the accretion and dissemination of antimicrobial-resistance …

Origin-of-transfer sequences facilitate mobilisation of non-conjugative antimicrobial-resistance plasmids in Staphylococcus aureus

FG O'Brien, K Yui Eto, RJT Murphy… - Nucleic acids …, 2015 - academic.oup.com
Staphylococcus aureus is a common cause of hospital, community and livestock-associated
infections and is increasingly resistant to multiple antimicrobials. A significant proportion of …

Staphylococcal plasmids, transposable and integrative elements

N Firth, SO Jensen, SM Kwong, RA Skurray… - Microbiology …, 2018 - Am Soc Microbiol
Strains of Staphylococcus aureus, and to a lesser extent other staphylococcal species, are a
significant cause of morbidity and mortality. An important factor in the notoriety of these …