Background Genetic studies have shown that C9orf72, SOD1, TARDBP and FUS are the
most common mutated genes in amyotrophic lateral sclerosis (ALS). Here, we performed a …

Amyotrophic lateral sclerosis is a progressive adult-onset neurodegenerative disease that
primarily affects upper and lower motor neurons, but also frontotemporal and other regions …

Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative disease
of motor neurons, resulting in worsening weakness of voluntary muscles until death from …

Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease. It is typically
fatal within 2–5 years of symptom onset. The incidence of ALS is largely uniform across most …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder of the motor pathways,
invariably leading to death within a few years of onset. Most cases of ALS are sporadic, but …

Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, is characterized
by the degeneration of both upper and lower motor neurons, which leads to muscle …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that results in
progressive loss of bulbar and limb function. Patients typically die from respiratory failure …

Hereditary amyotrophic lateral sclerosis (ALS) encompasses a group of genetic disorders
characterized by adult-onset loss of the lower and upper motor neuron systems, often with …

Background Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative
disease of upper and lower motor neurons, associated with frontotemporal dementia (FTD) …

Objective Amyotrophic lateral sclerosis (ALS) incidence rates are consistent with the
hypothesis that ALS is a multistep process. We tested the hypothesis that carrying a large …