During pregnancy, various immune effectors and molecules participating in the immune-
microenvironment establish specific maternal tolerance toward the semi-allogeneic fetus …

Cyclooxygenases-2 (COX-2) and Prostaglandin E2 (PGE2), which are important in chronic
inflammatory diseases, can increase tumor incidence and promote tumor growth and …

To commemorate the 50th anniversary of the Society of Toxicology, this special edition
article reviews the history and current scope of xenobiotic metabolism and transport, with …

The view of CD4 T‐cell‐mediated immunity as a balance between distinct lineages of Th1
and Th2 cells has changed dramatically. Identification of the IL‐17 family of cytokines and of …

Systemic juvenile idiopathic arthritis (sJIA) has long been recognized as unique among
childhood arthritides, because of its distinctive clinical and epidemiological features …

Introduction The aim of this study was to characterize interleukin 17 (IL-17) and interleukin
22 (IL-22) producing cells in peripheral blood (PB), skin, synovial fluid (SF) and synovial …

Introduction Accumulating evidence suggests an important role for interleukin 17 (IL-17) in
the pathogenesis of several inflammatory diseases, including rheumatoid arthritis (RA) and …

Osteoclasts are bone resorbing, multinucleate cells that differentiate from mononuclear
macrophage/monocyte-lineage hematopoietic precursor cells. Although previous studies …

Interleukin-26 (IL-26), a member of the IL-10 cytokine family, induces the production of
proinflammatory cytokines by epithelial cells. IL-26 has been also reported overexpressed in …

Background Vitiligo is a common skin disorder, characterized by progressive skin de-
pigmentation due to the loss of cutaneous melanocytes. The exact cause of melanocyte loss …