W Li, D Notani, MG Rosenfeld - Nature Reviews Genetics, 2016 - nature.com
Networks of regulatory enhancers dictate distinct cell identities and cellular responses to diverse signals by instructing precise spatiotemporal patterns of gene expression. However …
P Davis, M Zarowiecki, V Arnaboldi, A Becerra… - Genetics, 2022 - academic.oup.com
Abstract WormBase (www. wormbase. org) is the central repository for the genetics and genomics of the nematode Caenorhabditis elegans. We provide the research community …
CA Davis, BC Hitz, CA Sloan, ET Chan… - Nucleic acids …, 2018 - academic.oup.com
The Enc yclopedia of D NA E lements (ENCODE) Data Coordinating Center has developed the ENCODE Portal database and website as the source for the data and metadata …
TW Harris, V Arnaboldi, S Cain, J Chan… - Nucleic acids …, 2020 - academic.oup.com
Abstract WormBase (https://wormbase. org/) is a mature Model Organism Information Resource supporting researchers using the nematode Caenorhabditis elegans as a model …
To resolve cellular heterogeneity, we developed a combinatorial indexing strategy to profile the transcriptomes of single cells or nuclei, termed sci-RNA-seq (single-cell combinatorial …
The functional annotation of livestock genomes is crucial for understanding the molecular mechanisms that underpin complex traits of economic importance, adaptive evolution and …
Spatial localization is a key determinant of cellular fate and behavior, but methods for spatially resolved, transcriptome-wide gene expression profiling across complex tissues are …
Background JBrowse is a fast and full-featured genome browser built with JavaScript and HTML5. It is easily embedded into websites or apps but can also be served as a standalone …
Abstract The RNA polymerase II (Pol II) enzyme transcribes all protein-coding and most non- coding RNA genes and is globally regulated by Mediator—a large, conformationally flexible …