Machine learning approaches to drug response prediction: challenges and recent progress

G Adam, L Rampášek, Z Safikhani, P Smirnov… - NPJ precision …, 2020 - nature.com
Cancer is a leading cause of death worldwide. Identifying the best treatment using
computational models to personalize drug response prediction holds great promise to …

Systematic polypharmacology and drug repurposing via an integrated L1000-based Connectivity Map database mining

TP Liu, YY Hsieh, CJ Chou… - Royal Society open …, 2018 - royalsocietypublishing.org
Drug repurposing aims to find novel indications of clinically used or experimental drugs.
Because drug data already exist, drug repurposing may save time and cost, and bypass …