Circadian rhythms in haematological malignancies: therapeutic potential and personalised interventions
The circadian clock, a fundamental cellular mechanism, regulates the rhythmic expression of
numerous genes and biological processes across various organs. Disruptions in this …
numerous genes and biological processes across various organs. Disruptions in this …
A Review of the Effects of Some Extrinsic Factors on Mice Used in Research
AS Gozalo, WR Elkins - Comparative Medicine, 2023 - ingentaconnect.com
Animals have been used in research for over 2,000 y. From very crude experiments
conducted by ancient scholars, animal research, as a science, was refined over hundreds of …
conducted by ancient scholars, animal research, as a science, was refined over hundreds of …
Dim light at night shifts microglia to a pro-inflammatory state after cerebral ischemia, altering stroke outcome in mice
Circadian rhythms are endogenous biological cycles that regulate physiology and behavior
and are set to precisely 24-h by light exposure. Light at night (LAN) dysregulates physiology …
and are set to precisely 24-h by light exposure. Light at night (LAN) dysregulates physiology …
Chronic phase advances reduces recognition memory and increases vascular cognitive dementia-like impairments in aged mice
Disrupted or atypical light–dark cycles disrupts synchronization of endogenous circadian
clocks to the external environment; extensive circadian rhythm desynchrony promotes …
clocks to the external environment; extensive circadian rhythm desynchrony promotes …
Dim light at night promotes circadian disruption in female rats, at the metabolic, reproductive, and behavioral level
M Gutiérrez‐Pérez, S González‐González… - Advanced …, 2023 - Wiley Online Library
Inhabitants of urban areas are constantly exposed to light at night, which is an important
environmental factor leading to circadian disruption. Streetlights filtering light through the …
environmental factor leading to circadian disruption. Streetlights filtering light through the …
Melatonin, Light, and the Circadian System
ML Dubocovich - cambridge.org
The melatonin (5-methoxy-N-acetyltryptamine) molecule is synthesized and released
primarily from the pineal gland, and locally in the retina which relays the signal of darkness …
primarily from the pineal gland, and locally in the retina which relays the signal of darkness …