Polymeric micelles for the delivery of poorly soluble drugs: From nanoformulation to clinical approval
Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …
Exploiting developments in nanotechnology for the preferential delivery of platinum-based anti-cancer agents to tumours: targeting some of the hallmarks of cancer
JP Parker, Z Ude, CJ Marmion - Metallomics, 2016 - academic.oup.com
Platinum drugs as anti-cancer therapeutics are held in extremely high regard. Despite their
success, there are drawbacks associated with their use; their dose-limiting toxicity, their …
success, there are drawbacks associated with their use; their dose-limiting toxicity, their …
Novel platinum therapeutics induce rapid cancer cell death through triggering intracellular ROS storm
Induction of reactive oxygen species (ROS) production in cancer cells plays a critical role for
cancer treatment. However, therapeutic efficiency remains challenging due to insufficient …
cancer treatment. However, therapeutic efficiency remains challenging due to insufficient …
Novel poly (2-oxazoline) block copolymer with aromatic heterocyclic side chains as a drug delivery platform
Here we report a novel poly (2-oxazoline)-based block copolymer with the aromatic
heterocyclic side chains in one block, poly (2-methyl-2-oxazoline)-b-poly (2-N, N-dimethyl-1 …
heterocyclic side chains in one block, poly (2-methyl-2-oxazoline)-b-poly (2-N, N-dimethyl-1 …
Poly (2-Oxazoline)-Based Polymeric Micelle Platform for Drug Delivery
D Hwang - 2020 - search.proquest.com
Polymeric micelles (PMs) have been extensively utilized as drug delivery platform.
Particularly, potent hydrophobic small molecules were encapsulated in the PMs to alleviate …
Particularly, potent hydrophobic small molecules were encapsulated in the PMs to alleviate …