Protein cages: from fundamentals to advanced applications

TGW Edwardson, MD Levasseur, S Tetter… - Chemical …, 2022 - ACS Publications
Proteins that self-assemble into polyhedral shell-like structures are useful molecular
containers both in nature and in the laboratory. Here we review efforts to repurpose diverse …

[HTML][HTML] Nanotechnology in aquaculture: Applications, perspectives and regulatory challenges

C Fajardo, G Martinez-Rodriguez, J Blasco… - Aquaculture and …, 2022 - Elsevier
Aquaculture is considered one of the most important food production systems both in terms
of economic impact and food security, and the ongoing development of this industry is a key …

Self-assembling peptide dendron nanoparticles with high stability and a multimodal antimicrobial mechanism of action

Z Lai, Q Jian, G Li, C Shao, Y Zhu, X Yuan, H Chen… - ACS …, 2021 - ACS Publications
Self-assembling nanometer-scale structured peptide polymers and peptide dendrimers have
shown promise in biomedical applications due to their versatile properties and easy …

Antifouling and antibacterial behavior of membranes containing quaternary ammonium and zwitterionic polymers

MM Zhu, Y Fang, YC Chen, YQ Lei, LF Fang… - Journal of Colloid and …, 2021 - Elsevier
To overcome the organic-/bio-fouling of the membrane, a dual-functional ultrafiltration
membrane containing quaternary ammonium and zwitterionic polymers via quaternization …

Repurposing of the gold drug auranofin and a review of its derivatives as antibacterial therapeutics

Y Liu, Y Lu, Z Xu, X Ma, X Chen, W Liu - Drug Discovery Today, 2022 - Elsevier
Multidrug resistance (MDR) is a significant issue associated with the clinical application of
antibiotics. It is also challenging to discover and develop new antibiotics with novel …

Fast bacterial growth reduces antibiotic accumulation and efficacy

U Łapińska, M Voliotis, KK Lee, A Campey, MRL Stone… - Elife, 2022 - elifesciences.org
Phenotypic variations between individual microbial cells play a key role in the resistance of
microbial pathogens to pharmacotherapies. Nevertheless, little is known about cell …

Microfluidics for antibiotic susceptibility testing

W Postek, N Pacocha, P Garstecki - Lab on a Chip, 2022 - pubs.rsc.org
The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …

[HTML][HTML] Atomic force microscopy to elucidate how peptides disrupt membranes

K Hammond, MG Ryadnov… - Biochimica et Biophysica …, 2021 - Elsevier
Atomic force microscopy is an increasingly attractive tool to study how peptides disrupt
membranes. Often performed on reconstituted lipid bilayers, it provides access to time and …

Nutrient and salt depletion synergistically boosts glucose metabolism in individual Escherichia coli cells

G Glover, M Voliotis, U Łapińska, BM Invergo… - Communications …, 2022 - nature.com
The interaction between a cell and its environment shapes fundamental intracellular
processes such as cellular metabolism. In most cases growth rate is treated as a proximal …

Nontoxic and proteolytic-resistant self-assembled peptide dendrimer aggregates to combat multidrug-resistant gram-negative bacterial infections

Z Lai, X Yuan, G Li, H Chen, B Cheng… - Chemical Engineering …, 2024 - Elsevier
Peptide-based antimicrobial biomaterials hold considerable promise to treat the prevalent
infections caused by multidrug-resistant (MDR) pathogens. However, their clinical …