Neuromodulatory systems, including the noradrenergic, serotonergic, dopaminergic, and
cholinergic systems, track environmental signals, such as risks, rewards, novelty, effort, and …

Neurotransmitters are chemicals that are secreted by neurons and relay messages to target
cells. The goal of in vivo electrochemistry is to provide a real-time view of neurotransmitters …

We define the chemoconnectome (CCT) as the entire set of neurotransmitters,
neuromodulators, neuropeptides, and their receptors underlying chemotransmission in an …

Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …

[Frontiers in Bioscience 14, 5291-5338, June 1, 2009] 5291 Neurobiology of depression,
fibromyalgia and neuropathic pain Vladimi Page 1 [Frontiers in Bioscience 14, 5291-5338, June …

The neurotransmitter serotonin (5-HT), widely distributed in the central nervous system
(CNS), is involved in a large variety of physiological functions. In several brain regions 5-HT …

Since their discovery in the mammalian brain, it has been apparent that serotonin (5-HT)
and dopamine (DA) interactions play a key role in normal and abnormal behavior …

Rationale Activation of “co-agonist” N-methyl-d-aspartate (NMDA) and Glycine B sites is
mandatory for the operation of NMDA receptors, which play an important role in the control …

Behavioral activation that is associated with incentive-reward motivation increases in
adolescence relative to childhood and adulthood. This quadratic developmental pattern is …

Glutamate is the predominant excitatory neurotransmitter in the central nervous system
(CNS) and glutamatergic transmission is critical for controlling neuronal activity Glutamate is …