The oral cavity is inhibited by many of the bacterial species. Some of them have a key role in
the development of oral disease. Interrelationships between oral microbiome and systemic …

Protection against pathogens is a prerequisite for survival of most organisms. To cope with
this continuous challenge, complex defense mechanisms have evolved. The construction …

The effects of inflammatory cytokines on naive T cells have been studied using MHC
protein/peptide complexes on microspheres, thus avoiding the use of APCs whose functions …

Glaucoma is a widespread ocular disease characterized by a progressive loss of retinal
ganglion cells (RGCs). Previous studies suggest that the cytokine tumor necrosis factor-α …

Soluble tumour necrosis factor receptors (sTNF‐Rs) play a role as modulators of the
biological function of tumour necrosis factor‐α (TNF‐α) in an agonist/antagonist pattern. In …

Tumor necrosis factor alpha (TNFα) and lymphotoxin alpha (LTα) induce pleiotropic cellular
effects through low-affinity 55 kDa type-1 receptors (TNFR1, CD120a) and high-affinity 75 …

Like interleukin-1, recombinant human tumor necrosis factor α (TNFα) has been found to
decrease social exploration and induce weight loss in mice in a dose and time-dependent …

Peripheral administration of endotoxin induces brain-mediated responses, including
activation of the hypothalamus-pituitary-adrenal (HPA) axis and changes in …

Objective We evaluated C-reactive protein (C-RP), a quantitative marker of the acute phase
response, as a potential biomarker of prevalent and incident osteoarthritis of the knee (OAK) …

Background Asthma is a complex inflammatory disease which affects multiple individuals
worldwide especially pediatric ages. Aims This study aimed to assess the possible …