[HTML][HTML] Designing enhanced spray dried particles for inhalation: A review of the impact of excipients and processing parameters on particle properties

N Alhajj, NJ O'Reilly, H Cathcart - Powder Technology, 2021 - Elsevier
Spray drying is a constructive single-step manufacturing technique used to produce dry
powder. Spray drying plays a remarkable role in producing inhalable powder formulations …

Inhalation delivery for the treatment and prevention of COVID-19 infection

BB Eedara, W Alabsi, D Encinas-Basurto, R Polt… - Pharmaceutics, 2021 - mdpi.com
Coronavirus disease-2019 (COVID-19) is caused by coronavirus-2 (SARS-CoV-2) and has
produced a global pandemic. As of 22 June 2021, 178 million people have been affected …

[HTML][HTML] Spray-dried inhalable powder formulations of therapeutic proteins and peptides

BB Eedara, W Alabsi, D Encinas-Basurto, R Polt… - AAPS …, 2021 - Springer
Respiratory diseases are among the leading causes of morbidity and mortality worldwide.
Innovations in biochemical engineering and understanding of the pathophysiology of …

The future of dry powder inhaled therapy: Promising or discouraging for systemic disorders?

Y Ye, Y Ma, J Zhu - International journal of pharmaceutics, 2022 - Elsevier
Dry powder inhalation therapy has been shown to be an effective method for treating
respiratory diseases like asthma, Chronic Obstructive Pulmonary Diseases and Cystic …

Dry powder inhalers of antitubercular drugs

N Nainwal, Y Sharma, V Jakhmola - Tuberculosis, 2022 - Elsevier
Despite advancements in the medical and pharmaceutical fields, tuberculosis remains a
major health problem globally. Patients do not widely accept the conventional approach to …

Potential of dry powder inhalers for tuberculosis therapy: facts, fidelity and future

P Mehta, C Bothiraja, S Kadam… - … cells, nanomedicine, and …, 2018 - Taylor & Francis
Tuberculosis (TB) is a contagious and airborne infectious disease caused by the pathogen
Mycobacterium tuberculosis (Mtb). In spite of substantial research efforts, continuous …

Novel approaches for the treatment of pulmonary tuberculosis

ZM Tan, GP Lai, M Pandey, T Srichana, MR Pichika… - Pharmaceutics, 2020 - mdpi.com
Tuberculosis (TB) is a contagious airborne disease caused by Mycobacterium tuberculosis,
which primarily affects human lungs. The progression of drug-susceptible TB to drug …

Dissolution and absorption of inhaled drug particles in the lungs

BB Eedara, R Bastola, SC Das - Pharmaceutics, 2022 - mdpi.com
Dry powder inhalation therapy has been effective in treating localized lung diseases such
asthma, chronic obstructive pulmonary diseases (COPD), cystic fibrosis and lung infections …

High dose dry powder inhalers to overcome the challenges of tuberculosis treatment

MAM Momin, IG Tucker, SC Das - International journal of pharmaceutics, 2018 - Elsevier
Tuberculosis (TB) is a major global health burden. The emergence of the human
immunodeficiency virus (HIV) epidemic and drug resistance has complicated global TB …

The influence of surface active l-leucine and 1, 2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC) in the improvement of aerosolization of pyrazinamide and …

BB Eedara, B Rangnekar, C Doyle, A Cavallaro… - International journal of …, 2018 - Elsevier
Pharmacotherapy of tuberculosis is potentially more efficient when delivered by the inhaled
route than by the current oral and/or parenteral routes due to the higher concentration of …