Recent work in neuroscience has shown that the adult central nervous system contains
neural progenitors, precursors, and stem cells that are capable of generating new neurons …

Neural stem cells (NSCs) have great potential as a therapeutic tool for the repair of a
number of CNS disorders. NSCs can either be isolated from embryonic and adult brain …

Adult stem cells reside in unique niches that provide vital cues for their survival, self-renewal
and differentiation. In order to better understand the contribution of substrate stiffness to …

OBJECTIVE: Recent studies have shown that cells from bone marrow (BM), muscle, and
brain may have greater plasticity than previously known. We have identified multipotent …

With the explosion of knowledge from molecular biology and the burgeoning interest in
generating or regenerating tissues or organs through various bioengineering or stem cell …

Graft survival and integration are major factors that limit the efficacy of cell therapies for the
treatment of disease and injury in the central nervous system. Efforts to improve cell survival …

Proliferating populations of undifferentiated neural stem cells were isolated from the
embryonic day 14 rat cerebral cortex or the adult rat subventricular zone. These cells were …

Background Adult mesenchymal stem cells (MSCs) derived from adipose tissue have the
capacity to differentiate into mesenchymal as well as endodermal and ectodermal cell …

We recently showed that a rare cell from murine bone marrow, which we termed multipotent
adult progenitor cells (MAPCs), can be expanded for> 120 population doublings. Mouse (m) …

Pluripotent or multipotent stem cells isolated from human embryos or adult central nervous
system (CNS) may provide new neurons to ameliorate neural disorders. A major obstacle …