The IL-1 family of cytokines and receptors in rheumatic diseases

CA Dinarello - Nature Reviews Rheumatology, 2019 - nature.com
More than any other cytokine family, the 11 members of the IL-1 family are associated with
innate immune responses, which occur in acute inflammation and chronic inflammatory …

The IL-1 family cytokines and receptors in autoimmune diseases

P Migliorini, P Italiani, F Pratesi, I Puxeddu… - Autoimmunity …, 2020 - Elsevier
The role of the cytokines and receptors of the IL-1 family in inflammation is well known.
Several cytokines of the family have a powerful inflammatory activity, with IL-1β being the …

Cytokines in the pathogenesis of rheumatoid arthritis: new players and therapeutic targets

A Alunno, F Carubbi, R Giacomelli, R Gerli - BMC rheumatology, 2017 - Springer
In recent years, the landscape of pro-and anti-inflammatory cytokines has rapidly expanded
with the identification of new members proven to be involved at different extent in the …

[HTML][HTML] Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers

R López-Mejías, S Castañeda… - Autoimmunity …, 2016 - Elsevier
Cardiovascular disease (CV) is the most common cause of premature mortality in patients
with rheumatoid arthritis (RA). This is the result of an accelerated atherosclerotic process …

Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation

S Stojkovic, C Kaun, J Basilio, S Rauscher, L Hell… - Scientific reports, 2016 - nature.com
Tissue factor (TF) is the primary trigger of coagulation. Elevated levels of TF are found in
atherosclerotic plaques and TF leads to thrombus formation when released upon plaque …

Atherosclerotic cardiovascular risk stratification in the rheumatic diseases:: An integrative, multiparametric approach

DP Misra, EM Hauge, CS Crowson… - Rheumatic …, 2023 - rheumatic.theclinics.com
The rheumatic diseases are chronic systemic inflammatory syndromes affecting multiple
tissues and organs. Cardiovascular involvement represents either a main clinical …

The role of the IL-33/ST2 axis in autoimmune disorders: friend or foe?

X Liu, Y Xiao, Y Pan, H Li, SG Zheng, W Su - Cytokine & growth factor …, 2019 - Elsevier
Autoimmune diseases (ADs), which are common immune-mediated inflammatory
syndromes, are characterized by an imbalance between T effector (Th) 1/Th17 cells and T …

The paradigm change of IL-33 in vascular biology

S Demyanets, S Stojkovic, K Huber, J Wojta - International Journal of …, 2021 - mdpi.com
In this review, we focus on the actual understanding of the role of IL-33 in vascular biology in
the context of the historical development since the description of IL-33 as a member of IL-1 …

NFATc1-E2F1-LMCD1–Mediated IL-33 Expression by Thrombin Is Required for Injury-Induced Neointima Formation

S Govatati, P Pichavaram, J Janjanam… - … , and vascular biology, 2019 - Am Heart Assoc
Objective—IL (interleukin)-33 has been shown to play a role in endothelial dysfunction, but
its role in atherosclerosis is controversial. Therefore, the purpose of this study is to examine …

DAPSA, carotid plaque and cardiovascular events in psoriatic arthritis: a longitudinal study

SHM Lam, IT Cheng, EK Li, P Wong, J Lee… - Annals of the …, 2020 - ard.bmj.com
Objective To examine whether Disease Activity in Psoriatic Arthritis (DAPSA) reflecting the
inflammatory component of psoriatic arthritis (PsA) can predict cardiovascular (CV) events …