Amyotrophic lateral sclerosis

O Hardiman, A Al-Chalabi, A Chio, EM Corr… - Nature reviews Disease …, 2017 - nature.com
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, is characterized
by the degeneration of both upper and lower motor neurons, which leads to muscle …

Biomarkers in motor neuron disease: a state of the art review

NS Verber, SR Shepheard, M Sassani… - Frontiers in …, 2019 - frontiersin.org
Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The …

ESPEN guideline clinical nutrition in neurology

R Burgos, I Bretón, E Cereda, JC Desport, R Dziewas… - Clinical Nutrition, 2018 - Elsevier
Neurological diseases are frequently associated with swallowing disorders and malnutrition.
Moreover, patients with neurological diseases are at increased risk of micronutrient …

Correlation of peripheral immunity with rapid amyotrophic lateral sclerosis progression

BJ Murdock, T Zhou, SR Kashlan, RJ Little… - JAMA …, 2017 - jamanetwork.com
Importance Amyotrophic lateral sclerosis (ALS) has an immune component, but previous
human studies have not examined immune changes over time. Objectives To assess …

Blood biomarkers of carbohydrate, lipid, and apolipoprotein metabolisms and risk of amyotrophic lateral sclerosis: a more than 20‐year follow‐up of the Swedish …

D Mariosa, N Hammar, H Malmström… - Annals of …, 2017 - Wiley Online Library
Objective To assess the associations of blood biomarkers of carbohydrate, lipid, and
apolipoprotein metabolisms with the future risk of amyotrophic lateral sclerosis (ALS) …

Early weight loss in amyotrophic lateral sclerosis: outcome relevance and clinical correlates in a population-based cohort

C Moglia, A Calvo, M Grassano, A Canosa… - Journal of Neurology …, 2019 - jnnp.bmj.com
Objectives To assess the role of body mass index (BMI) and of the rate of weight loss as
prognostic factors in amyotrophic lateral sclerosis (ALS) and to explore the clinical correlates …

[HTML][HTML] What causes amyotrophic lateral sclerosis?

S Martin, A Al Khleifat, A Al-Chalabi - F1000Research, 2017 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis is a neurodegenerative disease predominantly affecting upper
and lower motor neurons, resulting in progressive paralysis and death from respiratory …

A longitudinal study defined circulating microRNAs as reliable biomarkers for disease prognosis and progression in ALS human patients

G Dobrowolny, J Martone, E Lepore, I Casola… - Cell death …, 2021 - nature.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with
motor neuron degeneration, muscle atrophy and paralysis. To date, multiple panels of …

Serum C-reactive protein as a prognostic biomarker in amyotrophic lateral sclerosis

C Lunetta, A Lizio, E Maestri, VA Sansone… - JAMA …, 2017 - jamanetwork.com
Importance Various factors have been proposed as possible candidates associated with the
prognosis of amyotrophic lateral sclerosis (ALS); however, there is still no consensus on …

ALS biomarkers for therapy development: state of the field and future directions

M Benatar, K Boylan, A Jeromin, SB Rutkove… - Muscle & …, 2016 - Wiley Online Library
Biomarkers have become the focus of intense research in the field of amyotrophic lateral
sclerosis (ALS), with the hope that they might aid therapy development efforts …