[HTML][HTML] Novel chemical permeation enhancers for transdermal drug delivery

Y Chen, P Quan, X Liu, M Wang, L Fang - Asian Journal of Pharmaceutical …, 2014 - Elsevier
Transdermal drug delivery has been accepted as a potential non-invasive route of drug
administration, with advantages of prolonged therapeutic action, decreased side effect, easy …

Current status of amino acid-based permeation enhancers in transdermal drug delivery

R Pereira, SG Silva, M Pinheiro, S Reis, ML Vale - Membranes, 2021 - mdpi.com
Transdermal drug delivery (TDD) presents many advantages compared to other
conventional routes of drug administration, yet its full potential has not been achieved. The …

Current development of chemical penetration enhancers for transdermal insulin delivery

V Sugumar, M Hayyan, P Madhavan, WF Wong… - Biomedicines, 2023 - mdpi.com
The use of the transdermal delivery system has recently gained ample recognition due to the
ability to deliver drug molecules across the skin membrane, serving as an alternative to …

Amphiphilic transdermal permeation enhancers: structure-activity relationships

K Vavrova, J Zbytovska… - Current medicinal …, 2005 - ingentaconnect.com
Transdermal drug delivery offers numerous advantages over conventional routes of
administration; however, poor permeation of most drugs across the skin barrier constitutes a …

A comparison of the in vitro permeation of niacinamide in mammalian skin and in the Parallel Artificial Membrane Permeation Assay (PAMPA) model

Y Zhang, ME Lane, J Hadgraft, M Heinrich… - International Journal of …, 2019 - Elsevier
The in vitro skin penetration of pharmaceutical or cosmetic ingredients is usually assessed
in human or animal tissue. However, there are ethical and practical difficulties associated …

State of the art in Stratum Corneum research: The biophysical properties of ceramides

T Schmitt, RHH Neubert - Chemistry and physics of lipids, 2018 - Elsevier
This review is summarizing an important part of the state of the art in stratum corneum
research. A complete overview on discoveries about the general biophysical and …

Novel skin permeation enhancers based on amino acid ester ionic liquid: Design and permeation mechanism

L Zheng, Z Zhao, Y Yang, Y Li, C Wang - International Journal of …, 2020 - Elsevier
This study developed novel ionic liquids (ILs) based on amino acids. We first screened 15
methyl amino acid ester hydrochlorides ([AAC1] Cl) for their skin permeation enhancements …

Amino acid lipids and uses thereof

SC Quay, ME Houston Jr, P Harvie, RC Adami… - US Patent …, 2014 - Google Patents
Mar. 30, 2011, now Pat. No. 8,501,824, which is a 6,869,788 132* 3/2005 Osabe
6131................... 435/227 division ofapplication No. 12/1 14,284,? led on May 2, 7,312,206 …

Application of sphingolipid-based nanocarriers in drug delivery: an overview

S Kumar, A Singh, P Pandey, A Khopade… - Therapeutic …, 2024 - Taylor & Francis
Sphingolipids (SL) are well recognized for their cell signaling through extracellular and
intracellular pathways. Based on chemistry different types of SL are biosynthesized in …

From Chitin to Bioactive Chitooligosaccharides and Conjugates: Access to Lipochitooligosaccharides and the TMG‐chitotriomycin

G Despras, A Alix, D Urban, B Vauzeilles… - Angewandte …, 2014 - Wiley Online Library
The direct and chemoselective N‐transacylation of peracetylated chitooligosaccharides
(COSs), readily obtained from chitin, to give per‐N‐trifluoroacetyl derivatives offers an …