The recent development of machine learning methods to identify peptides in complex mass
spectrometric data constitutes a major breakthrough in proteomics. Longstanding methods …

The Electrospray Ionization (ESI) is a soft ionization technique extensively used for
production of gas phase ions (without fragmentation) of thermally labile large …

Peptide fragmentation spectra are routinely predicted in the interpretation of mass-
spectrometry-based proteomics data. However, the generation of fragment ions has not …

Hydrogen/deuterium exchange (HDX) mass spectrometry (MS) has become a key technique
for monitoring structural and dynamic aspects of proteins in solution. This approach relies on …

This work experimentally verifies and proves the two long since postulated matrix-assisted
laser desorption/ionization (MALDI) analyte protonation pathways known as the Lucky …

Electrospray ionization (ESI) is an essential technique for transferring proteins from solution
into the gas phase for mass spectrometry and ion mobility spectrometry. The mechanisms …

In proteomics, de novo sequencing is the process of deriving peptide sequences from
tandem mass spectra without the assistance of a sequence database. Such analyses have …

Complete self-assembly and reassembly behavior of bitter peptide-protein necessitates
multilevel theories that encompass phenomena ranging from the self-assembly of …

Mass‐spectrometry coupled to liquid chromatography is an indispensable tool in the field of
proteomics. In the last decades, more and more complex and diverse biochemical and …

Experiments and molecular dynamics (MD) simulations in the literature indicate that
gaseous proteins generated by electrospray ionization (ESI) can retain native-like structures …