Use of PCR in the field of molecular diagnostics has increased to the point where it is now
accepted as the standard method for detecting nucleic acids from a number of sample and …

The efficient characterization of genetic and epigenetic alterations in oncology, virology, or
prenatal diagnostics requires highly sensitive and specific high-throughput approaches …

Antiretroviral treatment (ART) of HIV infection suppresses viral replication. Yet if ART is
stopped, virus reemerges because of the persistence of infected cells. We evaluated the …

To understand the high variability of the asymptomatic interval between primary human
immunodeficiency virus type 1 (HIV-1) infection and the development of AIDS, we studied …

The HIV-1 epidemic in sub-Saharan Africa is driven largely by heterosexual transmission of
non-subtype B viruses, of which subtypes C and A are predominant. Previous studies of …

In vitro studies show that human immunodeficiency virus type 1 (HIV-1) does not replicate in
freshly isolated monocytes unless monocytes differentiate to monocyte-derived …

Immune responses induced during the early stages of chronic viral infections are thought to
influence disease outcome. Using HIV as a model, we examined virus-specific cytotoxic T …

Episodes of low-level viremia (LLV), with plasma human immunodeficiency virus type 1 (HIV-
1) RNA levels ranging from 50 to 400 copies (c)/ml, occur commonly during highly active …

The quantity of Borrelia burgdorferi organisms in tissue samples is an important determinant
for infection studies in the mouse model of Lyme disease. This report presents the …

Recombinants of preexisting human immunodeficiency virus type 1 (HIV-1) strains are now
circulating globally. To increase our understanding of the importance of these recombinants …