Recent advances in DNA origami-engineered nanomaterials and applications

P Zhan, A Peil, Q Jiang, D Wang, S Mousavi… - Chemical …, 2023 - ACS Publications
DNA nanotechnology is a unique field, where physics, chemistry, biology, mathematics,
engineering, and materials science can elegantly converge. Since the original proposal of …

Mechanics of dynamic and deformable DNA nanostructures

R Li, AS Madhvacharyula, Y Du, HK Adepu… - Chemical Science, 2023 - pubs.rsc.org
In DNA nanotechnology, DNA molecules are designed, engineered, and assembled into
arbitrary-shaped architectures with predesigned functions. Static DNA assemblies often …

Translocation of specific DNA nanocarrier through an ultrasmall nanopipette: toward single-protein-molecule detection with superior signal-to-noise ratio

X Zhang, D Luo, YW Zheng, XQ Li, J Song, WW Zhao… - ACS …, 2022 - ACS Publications
The use of functional DNA nanostructures as carriers to ship proteins through solid-state
nanopores has recently seen substantial growth in single-protein-molecule detection …

Versatile computer-aided design of free-form DNA nanostructures and assemblies

WG Pfeifer, CM Huang, MG Poirier, G Arya… - Science …, 2023 - science.org
Recent advances in structural DNA nanotechnology have been facilitated by design tools
that continue to push the limits of structural complexity while simplifying an often-tedious …

Localized plasmonic heating for single-molecule DNA rupture measurements in optical tweezers

P Kabtiyal, A Robbins, E Jergens, CE Castro… - Nano Letters, 2024 - ACS Publications
To date, studies on the thermodynamic and kinetic processes that underlie biological
function and nanomachine actuation in biological-and biology-inspired molecular constructs …

Accelerating the characterization of dynamic DNA origami devices with deep neural networks

Y Wang, X Jin, C Castro - Scientific Reports, 2023 - nature.com
Mechanical characterization of dynamic DNA nanodevices is essential to facilitate their use
in applications like molecular diagnostics, force sensing, and nanorobotics that rely on …

Steric communication between dynamic components on DNA nanodevices

Y Wang, S Sensale, M Pedrozo, CM Huang… - ACS …, 2023 - ACS Publications
Biomolecular nanotechnology has helped emulate basic robotic capabilities such as defined
motion, sensing, and actuation in synthetic nanoscale systems. DNA origami is an attractive …

Mechanical DNA origami to investigate biological systems

A Mills, N Aissaoui, J Finkel, J Elezgaray… - Advanced …, 2023 - Wiley Online Library
The ability to self‐assemble DNA nanodevices with programmed structural dynamics that
can sense and respond to the local environment can enable transformative applications in …

Cooperative control of a DNA origami force sensor

A Robbins, H Hildebolt, M Neuhoff, P Beshay… - Scientific Reports, 2024 - nature.com
Biomolecular systems are dependent on a complex interplay of forces. Modern force
spectroscopy techniques provide means of interrogating these forces, but they are not …

Energy landscapes of rotary DNA origami devices determined by fluorescence particle tracking

A Büchl, E Kopperger, M Vogt, M Langecker… - Biophysical …, 2022 - cell.com
Biomolecular nanomechanical devices are of great interest as tools for the processing and
manipulation of molecules, thereby mimicking the function of nature's enzymes. DNA …