Plant Soup Formulations Show Cholinesterase Inhibition Potential in the Prevention of Alzheimer's Disease

D Gajowniczek-Ałasa, D Szwajgier… - Current Alzheimer …, 2024 - benthamdirect.com
Background: As the cholinesterase theory is a prominent hypothesis underlying our current
understanding of Alzheimer's disease (AD), the goal of this study was to compose functional …

[HTML][HTML] Mechanistic and Therapeutic Insights into Flavonoid-Based Inhibition of Acetylcholinesterase: Implications for Neurodegenerative Diseases

N Cichon, W Grabowska, L Gorniak, M Stela… - Nutrients, 2024 - mdpi.com
Flavonoids are naturally occurring polyphenolic compounds known for their extensive range
of biological activities. This review focuses on the inhibitory effects of flavonoids on …

Metabolomics-guided discrimination of constituents in five commercial apple (Malus× domestica Borkh.) cultivars: Assessment of their antioxidant, neuroprotective …

S Fayez, OA Eldahshan, N Nilofar, G Zengin… - Food Bioscience, 2024 - Elsevier
Abstract Apples (Malus× domestica Borkh.) are available in different cultivars, we
investigated the similarities and differences in the chemical composition and biological …

[HTML][HTML] Mechanism of baixiangdan capsules on anti-neuroinflammation: combining dry and wet experiments

Q Yu, M Liu, T Zhao, M Su, S Wang, W Xu, S He… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Neuroinflammation plays an important role in the pathogenesis of neurological disorders,
and despite intensive research, treatment of neuroinflammation remains limited …

Computational Molecular Docking and Simulation-Based Assessment of Anti-Inflammatory Properties of Nyctanthes arbor-tristis Linn Phytochemicals

V Ahmad, MI Khan, QMS Jamal, FA Alzahrani… - Pharmaceuticals, 2023 - mdpi.com
The leaves, flowers, seeds, and bark of the Nyctanthes arbor-tristis Linn plant have been
pharmacologically evaluated to signify the medicinal importance traditionally described for …

Selected phytochemicals as potent acetylcholinesterase inhibitors: An in silico prediction

RLS Shrestha, P Neupane, S Dhital… - Journal of the Serbian …, 2024 - doiserbia.nb.rs
In recent times, there has been a notable increase in the prevalence of Alzheimer's disease.
The disease could be managed through the inhibition of acetylcholinesterase, an enzyme …

Vegan and Vegetarian Soups Are Excellent Sources of Cholinesterase Inhibitors

D Gajowniczek-Ałasa, E Baranowska-Wójcik… - Nutrients, 2024 - mdpi.com
Background: The cholinesterase theory stands as the most popular worldwide therapy for
Alzheimer's disease (AD). Given the absence of a cure for AD, a plant-based diet has been …

Investigating the Antiviral Properties of Nyctanthes arbor-tristis Linn against the Ebola, SARS-CoV-2, Nipah, and Chikungunya Viruses: A Computational Simulation …

R Albiheyri, V Ahmad, MI Khan, FA Alzahrani… - Pharmaceuticals, 2024 - mdpi.com
Background: The hunt for naturally occurring antiviral compounds to combat viral infection
was expedited when COVID-19 and Ebola spread rapidly. Phytochemicals from Nyctanthes …

Computational Approaches to Evaluate the Acetylcholinesterase Binding Interaction with Taxifolin for the Management of Alzheimer's Disease

V Ahmad, I Alotibi, AA Alghamdi, A Ahmad, QMS Jamal… - Molecules, 2024 - mdpi.com
Acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are enzymes that break
down and reduce the level of the neurotransmitter acetylcholine (ACh). This can cause a …

Identification of Metabolites from Catharanthus roseus Leaves and Stem Extract, and In Vitro and In Silico Antibacterial Activity against Food Pathogens

QMS Jamal, V Ahmad - Pharmaceuticals, 2024 - mdpi.com
The plant produced powerful secondary metabolites and showed strong antibacterial
activities against food-spoiling bacterial pathogens. The present study aimed to evaluate …