Abstract Fibroblast growth factor (FGF) 2, FGF4, FGF7 and FGF20 are representative
paracrine FGFs binding to heparan-sulfate proteoglycan and fibroblast growth factor …

Background Angiogenesis is the process of neovascularization from pre-existing
vasculature and is involved in various physiological and pathological processes. Inhibitors …

Formononetin, an isoflavone, is extracted from various medicinal plants and herbs, including
the red clover (Trifolium pratense) and Chinese medicinal plant Astragalus membranaceus …

Collagen peptides can promote wound healing and are closely related to microbiome
colonization. We investigated the relationship among collagen peptides, wound healing …

Tumour vasculature is generally disordered because of the production of excessive
angiogenic factors by tumour cells, which results in tumour progression and reduces the …

Radiotherapy (RT) as one of the most powerful cancer treatment strategies has been greatly
restricted by tumor hypoxia. A mounting effort has been devoted to develop oxygen delivery …

Most anti-angiogenic therapies currently being evaluated in clinical trials target vascular
endothelial growth factor (VEGF) pathway, however, the tumor vasculature can acquire …

Endostatin (ES) can effectively inhibit neovascularization in most solid tumors and has the
potential to make oxygen delivery more efficient and increase the efficacy of radiotherapy …

Endostatin, a protein derived from the cleavage of collagen XVIII by the action of proteases,
is an endogenous inhibitor known for its ability to inhibit proliferation and migration of …

Fibroblast growth factors (FGFs) are pleiotropic molecules exerting autocrine, intracrine and
paracrine functions via activating four tyrosine kinase FGF receptors (FGFR), which further …