The analysis of the absolute configuration, enantiomeric composition, and concentration of
chiral compounds are frequently encountered tasks across the chemical and health …

Conspectus Stereochemistry is a fundamental molecular property with important
ramifications for structure, function, and activity of organic molecules. The basic building …

This Perspective highlights the advances of optical methods for asymmetric reaction
discovery. Optical analysis allows for the determination of absolute configuration …

Chiral epoxides are important intermediates in chemistry and biology. The high-throughput
screening of asymmetric epoxidation conditions requires fast determination of the absolute …

Chiroptical sensing of nitriles is achieved with excellent functional group tolerance by
hydrozirconation and subsequent transmetalation of the corresponding iminate to a …

Enantiomeric excess (ee) determination is crucial in many aspects of science, from synthesis
to materials. Within this subject, coupling molecular sensors with chiroptical techniques is a …

Achiral chromophoric hosts, ie acyclic cucurbit [n] urils and molecular tweezers, were found
to respond with characteristic Circular Dichroism (CD) spectra to the presence of micromolar …

Broadly useful chiroptical enantiomeric excess (ee) sensing remains challenging and
typically involves carefully designed molecular receptors or supramolecular assemblies …

Chirality sensing of choline derivatives is achieved by a self-assembled, racemic triple anion
helicate cage which exhibits induced circular dichroism (ICD) upon encapsulation of a chiral …

We have reported here the complexation and chiroptical behavior of the host–guest
complexes using a new chiral Zn (II) bisporphyrin tweezer host and a series of achiral …