The older adult brain is less modular, more integrated, and less efficient at rest: A systematic review of large‐scale resting‐state functional brain networks in aging

HA Deery, R Di Paolo, C Moran, GF Egan… - …, 2023 - Wiley Online Library
The literature on large‐scale resting‐state functional brain networks across the adult
lifespan was systematically reviewed. Studies published between 1986 and July 2021 were …

Functional brain connectivity changes across the human life span: From fetal development to old age

M Edde, G Leroux, E Altena… - Journal of neuroscience …, 2021 - Wiley Online Library
The dynamic of the temporal correlations between brain areas, called functional connectivity
(FC), undergoes complex transformations through the life span. In this review, we aim to …

[HTML][HTML] Functional network reorganization in older adults: Graph-theoretical analyses of age, cognition and sex

J Stumme, C Jockwitz, F Hoffstaedter, K Amunts… - NeuroImage, 2020 - Elsevier
Healthy aging has been associated with a decrease in functional network specialization.
Importantly, variability of alterations of functional connectivity is especially high across older …

[HTML][HTML] From swing to cane: sex differences of EEG resting-state temporal patterns during maturation and aging

MI Tomescu, TA Rihs, V Rochas, M Hardmeier… - Developmental cognitive …, 2018 - Elsevier
While many insights on brain development and aging have been gained by studying resting-
state networks with fMRI, relating these changes to cognitive functions is limited by the …

Simultaneous resting-state FDG-PET/fMRI in Alzheimer disease: relationship between glucose metabolism and intrinsic activity

R Marchitelli, M Aiello, A Cachia, M Quarantelli… - Neuroimage, 2018 - Elsevier
Simultaneously evaluating resting-state brain glucose metabolism and intrinsic functional
activity has potential to impact the clinical neurosciences of Alzheimer Disease (AD). Indeed …

The retrosplenial cortex: A memory gateway between the cortical default mode network and the medial temporal lobe

N Kaboodvand, L Bäckman, L Nyberg… - Human brain …, 2018 - Wiley Online Library
The default mode network (DMN) involves interacting cortical areas, including the posterior
cingulate cortex (PCC) and the retrosplenial cortex (RSC), and subcortical areas, including …

[HTML][HTML] Deep learning for sex classification in resting-state and task functional brain networks from the UK Biobank

M Leming, J Suckling - NeuroImage, 2021 - Elsevier
Classification of whole-brain functional connectivity MRI data with convolutional neural
networks (CNNs) has shown promise, but the complexity of these models impedes …

[HTML][HTML] Sex differences in neuroimmunoendocrine communication. Involvement on longevity

LM Suarez, E Diaz-Del Cerro, J Felix… - Mechanisms of ageing …, 2023 - Elsevier
Endocrine, nervous, and immune systems work coordinately to maintain the global
homeostasis of the organism. They show sex differences in their functions that, in turn …

Age-and gender-related dispersion of brain networks across the lifespan

Q Wang, L Qi, C He, H Feng, C Xie - Geroscience, 2024 - Springer
The effects of age and gender on large-scale resting-state networks (RSNs) reflecting within-
and between-network connectivity in the healthy brain remain unclear. This study …

The aging trajectories of brain functional hierarchy and its impact on cognition across the adult lifespan

X Wang, CC Huang, SJ Tsai, CP Lin… - Frontiers in Aging …, 2024 - frontiersin.org
Introduction The hierarchical network architecture of the human brain, pivotal to cognition
and behavior, can be explored via gradient analysis using restingstate functional MRI data …