How we treat NK/T-cell lymphomas

E Tse, WL Zhao, J Xiong, YL Kwong - Journal of hematology & oncology, 2022 - Springer
Abstract Natural killer (NK)/T-cell lymphomas are aggressive malignancies with a
predilection for Asian and South American populations. Epstein–Barr virus (EBV) infection in …

NK-/T-cell lymphomas

H Wang, B Fu, RP Gale, Y Liang - Leukemia, 2021 - nature.com
Natural killer/T-cell lymphoma (NKTL) is a sub-type of Epstein–Barr virus (EBV)-related non-
Hodgkin lymphomas common in Asia and Latin America but rare elsewhere. Its …

Genomic profiling for clinical decision making in lymphoid neoplasms

L De Leval, AA Alizadeh, PL Bergsagel… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

Peripheral T cell lymphomas: from the bench to the clinic

D Fiore, LV Cappelli, A Broccoli, PL Zinzani… - Nature Reviews …, 2020 - nature.com
Peripheral T cell lymphomas (PTCLs) are a heterogeneous group of orphan neoplasms.
Despite the introduction of anthracycline-based chemotherapy protocols, with or without …

Molecular pathogenic pathways in extranodal NK/T cell lymphoma

S de Mel, SSS Hue, AD Jeyasekharan… - Journal of hematology & …, 2019 - Springer
Extranodal NK/T cell lymphoma, nasal type (ENKTL) is an aggressive malignancy with a
dismal prognosis. Although l-asparaginase-based chemotherapy has resulted in improved …

Genomic and transcriptomic landscapes of Epstein-Barr virus in extranodal natural killer T-cell lymphoma

RJ Peng, BW Han, QQ Cai, XY Zuo, T Xia, JR Chen… - Leukemia, 2019 - nature.com
Extranodal natural killer T-cell lymphoma (nasal type; NKTCL) is an aggressive malignancy
strongly associated with Epstein-Barr virus (EBV) infection. However, the role of EBV in …

Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma

JQ Lim, D Huang, T Tang, D Tan, Y Laurensia… - Leukemia, 2020 - nature.com
Antibodies targeting the immune checkpoint axis have been approved by the FDA for the
treatment of a broad range of malignancies [1]. NKTCL is an aggressive hematological …

Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study in multiple populations

GW Lin, C Xu, K Chen, HQ Huang, J Chen… - The Lancet …, 2020 - thelancet.com
Background Extranodal natural killer T-cell lymphoma (NKTCL; nasal type) is an aggressive
malignancy with a particularly high prevalence in Asian and Latin American populations …

NK/T-cell lymphomas

E Tse, YL Kwong - Best Practice & Research Clinical Haematology, 2019 - Elsevier
NK/T-cell lymphomas are extranodal EBV-related malignancies, mostly of NK-cell and
occasionally of T-cell lineage. They are divided into nasal, non-nasal, and disseminated …

EBV in T-/NK-cell tumorigenesis

H Kimura - Human Herpesviruses, 2018 - Springer
Abstract Epstein–Barr virus (EBV), which is associated with B-cell proliferative disorders,
also transforms T-or natural killer (NK)-lineage cells and has been connected with various T …