Chronic traumatic encephalopathy (CTE): criteria for neuropathological diagnosis and relationship to repetitive head impacts
Over the last 17 years, there has been a remarkable increase in scientific research
concerning chronic traumatic encephalopathy (CTE). Since the publication of NINDS–NIBIB …
concerning chronic traumatic encephalopathy (CTE). Since the publication of NINDS–NIBIB …
National Institute of Neurological Disorders and Stroke consensus diagnostic criteria for traumatic encephalopathy syndrome
Objective To develop evidence-informed, expert consensus research diagnostic criteria for
traumatic encephalopathy syndrome (TES), the clinical disorder associated with …
traumatic encephalopathy syndrome (TES), the clinical disorder associated with …
Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies
Loss of nuclear TDP-43 is a hallmark of neurodegeneration in TDP-43 proteinopathies,
including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). TDP-43 …
including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). TDP-43 …
LATE-NC staging in routine neuropathologic diagnosis: an update
An international consensus report in 2019 recommended a classification system for limbic-
predominant age-related TDP-43 encephalopathy neuropathologic changes (LATE-NC) …
predominant age-related TDP-43 encephalopathy neuropathologic changes (LATE-NC) …
Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules
B Falcon, J Zivanov, W Zhang, AG Murzin, HJ Garringer… - Nature, 2019 - nature.com
Chronic traumatic encephalopathy (CTE) is a neurodegenerative tauopathy that is
associated with repetitive head impacts or exposure to blast waves. First described as punch …
associated with repetitive head impacts or exposure to blast waves. First described as punch …
The second NINDS/NIBIB consensus meeting to define neuropathological criteria for the diagnosis of chronic traumatic encephalopathy
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disorder associated with
exposure to head trauma. In 2015, a panel of neuropathologists funded by the NINDS/NIBIB …
exposure to head trauma. In 2015, a panel of neuropathologists funded by the NINDS/NIBIB …
A fluid biomarker reveals loss of TDP-43 splicing repression in presymptomatic ALS–FTD
KE Irwin, P Jasin, KE Braunstein, IR Sinha, MA Garret… - Nature medicine, 2024 - nature.com
Although loss of TAR DNA-binding protein 43 kDa (TDP-43) splicing repression is well
documented in postmortem tissues of amyotrophic lateral sclerosis (ALS) and frontotemporal …
documented in postmortem tissues of amyotrophic lateral sclerosis (ALS) and frontotemporal …
Cellular and pathological heterogeneity of primary tauopathies
DC Chung, S Roemer, L Petrucelli… - Molecular …, 2021 - Springer
Microtubule-associated protein tau is abnormally aggregated in neuronal and glial cells in a
range of neurodegenerative diseases that are collectively referred to as tauopathies …
range of neurodegenerative diseases that are collectively referred to as tauopathies …
The far-reaching scope of neuroinflammation after traumatic brain injury
DW Simon, MJ McGeachy, H Bayır, RSB Clark… - Nature Reviews …, 2017 - nature.com
The'silent epidemic'of traumatic brain injury (TBI) has been placed in the spotlight as a result
of clinical investigations and popular press coverage of athletes and veterans with single or …
of clinical investigations and popular press coverage of athletes and veterans with single or …
[HTML][HTML] RNA binding antagonizes neurotoxic phase transitions of TDP-43
TDP-43 proteinopathy is a pathological hallmark of amyotrophic lateral sclerosis and
frontotemporal dementia where cytoplasmic TDP-43 inclusions are observed within …
frontotemporal dementia where cytoplasmic TDP-43 inclusions are observed within …