The brain is well protected against microbial invasion by cellular barriers, such as the blood-
brain barrier (BBB) and the blood-cerebrospinal fluid barrier (BCSFB). In addition, cells …

Naegleria fowleri is a free-living amoeba (FLA) that is commonly known as the “brain-eating
amoeba.” This parasite can invade the central nervous system (CNS), causing an acute and …

The olfactory mucosa is a component of the nasal airway that mediates the sense of smell.
Recent studies point to an important role for the olfactory mucosa as a barrier to both …

Naegleria fowleri is a protist pathogen that can cause lethal brain infection. Despite decades
of research, the mortality rate related with primary amoebic meningoencephalitis owing to N …

First discovered in 1899, Naegleria fowleri is a protist pathogen, known to infect the central
nervous system and produce primary amoebic meningoencephalitis. The most distressing …

Background This cross-sectional study aimed to investigate the current prevalence and risk
factors associated with intestinal polyparasitism (the concurrent infection with multiple …

Naegleria fowleri is a thermophilic, free-living ameba that causes primary amebic
meningoencephalitis. The infections are nearly always fatal. We present the third well …

Diseases caused by pathogenic free-living amoebae include primary amoebic
meningoencephalitis (Naegleria fowleri), granulomatous amoebic encephalitis …

The epithelium represents the first and most extensive line of defence against pathogens,
toxins and pollutant agents in humans. In general, pathogens have developed strategies to …

Among various genera of free-living amoebae prevalent in nature, some members are
identified as causative agents of human encephalitis, in which Naegleria fowleri followed by …