Muscle spindles encode mechanosensory information by mechanisms that remain only
partially understood. Their complexity is expressed in mounting evidence of various …

Our objective was to evaluate an ex vivo muscle–nerve preparation used to study
mechanosensory signalling by low threshold mechanosensory receptors (LTMRs) …

Genetic variation is a well-known contributor to the onset and progression of cancer. The
goal of this study is to provide a comprehensive examination of the nucleotide and …

Oxaliplatin (OX) chemotherapy can lead to long-term sensorimotor impairments in cancer
survivors. The impairments are often thought to be caused by OX-induced progressive …

Injury that severs peripheral nerves often results in long-lasting motor behavioral deficits and
in reorganization of related spinal motor circuitry, neither of which reverse even after nerve …

Persistent sensory, motor and cognitive disabilities comprise chemotherapy-induced neural
disorders (CIND) that limit quality of life with little therapeutic relief for cancer survivors. Our …

Background Oxaliplatin (OX) chemotherapy for colorectal cancer is associated with adverse
neurotoxic effects that can contribute to long-term sensorimotor impairments in cancer …

Background Dual-task function is compromised among individuals with prodromal
Alzheimer's disease (AD) and others at risk of developing AD. While exercise has been …

Background Taxanes such as paclitaxel (PTX) induce dose-dependent chemotherapy-
induced peripheral neuropathy (CIPN), which is associated with debilitating chronic pain …

Cutaneous feedback from feet is involved in regulation of muscle activity during locomotion,
and the lack of this feedback results in motor deficits. We tested the hypothesis that …