The role of brain-derived neurotrophic factor in immune-related diseases: a narrative review

M Sochal, M Ditmer, A Gabryelska… - Journal of Clinical …, 2022 - mdpi.com
Brain-derived neurotrophic factor (BDNF) is a neurotrophin regulating synaptic plasticity,
neuronal excitability, and nociception. It seems to be one of the key molecules in interactions …

What do we know about nociplastic pain?

K Bułdyś, T Górnicki, D Kałka, E Szuster… - Healthcare, 2023 - mdpi.com
Nociplastic pain is a recently distinguished type of pain, distinct from neuropathic and
nociceptive pain, and is well described in the literature. It is often mistaken for central …

The role of the brain-derived neurotrophic factor in chronic pain: links to central sensitization and neuroinflammation

HY Xiong, J Hendrix, S Schabrun, A Wyns… - Biomolecules, 2024 - mdpi.com
Chronic pain is sustained, in part, through the intricate process of central sensitization (CS),
marked by maladaptive neuroplasticity and neuronal hyperexcitability within central pain …

Pain biomarkers in fibromyalgia syndrome: current understanding and future directions

M Favretti, C Iannuccelli, M Di Franco - International Journal of Molecular …, 2023 - mdpi.com
Fibromyalgia is a complex and heterogeneous clinical syndrome, mainly characterized by
the presence of widespread pain, possibly associated with a variety of other symptoms …

Brain-derived neurotrophic factor in fibromyalgia: A systematic review and meta-analysis of its role as a potential biomarker

AH Behnoush, A Khalaji, S Khanmohammadi… - Plos one, 2023 - journals.plos.org
Background Fibromyalgia (FM) is a form of chronic pain disorder accompanied by several
tender points, fatigue, sleeping and mood disturbances, cognitive dysfunction, and memory …

Efficacy of home-based transcranial direct current stimulation over the primary motor cortex and dorsolateral prefrontal cortex in the disability due to pain in …

W Caumo, RL Ramos, PV Serrano… - The journal of pain, 2024 - Elsevier
This randomized, double-blind, controlled clinical trial compared the effectiveness of home-
based-(HB) active transcranial direct current stimulation (a-tDCS) over the left dorsolateral …

[HTML][HTML] Tantali fibromyalgic supplicium: Is there any relief with the antidepressant employment? A systematic review

S Ilari, LC Passacatini, V Malafoglia… - Pharmacological …, 2022 - Elsevier
Widespread musculoskeletal pain characterizes fibromyalgia (FM), accompanied by sleep,
fatigue, and mood problems. Chronic stress and depression play a crucial role in the …

Differences in Plasma BDNF Levels Between Chronic Primary Musculoskeletal Pain, Fibromyalgia Syndrome, and Asymptomatic Subjects: A Cross-Sectional Study

DB Silvia, GÁ Francisco, RV Álvaro… - Biological Research …, 2025 - journals.sagepub.com
This cross-sectional study compared plasma brain-derived neurotrophic factor (BDNF)
levels among chronic primary musculoskeletal pain patients, chronic widespread pain …

Comparing the Effects of High and Moderate Intensity Exercise on Male and Female Rats with and without PTSD: A Behavioral and Biochemical Study

S Shafia, E Ghadirzadeh… - … of Medical Sciences, 2023 - jmums.mazums.ac.ir
Background and purpose: Post-traumatic stress disorder (PTSD) is a condition that occurs in
some people after experiencing shocking events. In this disorder, the function of some …

The putative role of immune-inflammatory mechanisms in nociplastic pain pathways: a narrative review

M Giglio, A Corriero, A Preziosa… - Exploration of …, 2025 - explorationpub.com
Nociplastic pain is the fourth category of pain defined in recent years. It is a pain arising from
altered nociception, despite the lack of clear evidence of actual or threatened tissue damage …