Alzheimer's disease acknowledged as progressive multifarious neurodegenerative disorder,
is the leading cause of dementia in late adult life. Pathologically it is characterized by …

Tobacco smoking is an extremely addictive and harmful form of nicotine (NIC) consumption,
but unfortunately also the most prevalent. Although disproportionately high frequencies of …

The aim of the present study is to evaluate the status of plasma essential trace elements
magnesium (Mg), copper (Cu), zinc (Zn), iron (Fe) and selenium (Se) concentrations and …

Alzheimer's disease (AD) was first described and diagnosed by Dr. Alois Alzheimer in 1906
(Hippius and Neundorfer, Dialogues Clin Neurosc 5: 101–108, 2003). According to World …

Alzheimer´ s disease (AD) is a progressive neurodegenerative dementia which currently
represents one of the biggest threats for the human kind. The cure is still unknown and …

Phloretin (PHL), a dihydrochalcone flavonoid usually present in the roots and leaves of
apple tree. In vitro study on GT1-7 immortalized hypothalamic neurons exposed to amyloid …

Among possible markers of age-related cognitive decline, uric acid (UA) is controversial
because it has antioxidant properties but is increased in diseases that often lead to cognitive …

Alzheimer's disease (AD) is a significant health crisis, and current treatments provide only
limited benefits to cognition at the cost of serious side effects. Recently, virtual screening …

Abstract Secretory phospholipase A 2-IIA (sPLA 2-IIA) is an inflammatory protein known to
play a role in the pathogenesis of many inflammatory diseases. Although this enzyme has …

Classic hypotheses of Alzheimer's disease (AD) include cholinergic neuron death,
acetylcholine (ACh) deficiency, metal ion dynamic equilibrium disorder, and deposition of …