BACKGROUND Vascular replacement and repair for the treatment of atherosclerotic
disease, infection, and traumatic injury are some of the most commonly performed surgical …

Adaptive as well as innate immune responses contribute to the development of
atherosclerosis. Studies performed in experimental animals have revealed that some of …

MXene nanomaterials have sparked significant interest among interdisciplinary researchers
to tackle today's medical challenges. In particular, colloidal MXene quantum dots (MQDs) …

Background: Coronary allograft vasculopathy (CAV) is a devastating sequela of heart
transplant in which arterial intimal thickening limits coronary blood flow. There are currently …

MXenes are an emerging class of nanomaterials with significant potential for applications in
nanomedicine. Amongst MXene technologies, titanium carbide (Ti 3 C 2 T x) nanomaterials …

Rationale: Transplantation-accelerated arteriosclerosis is one of the major challenges for
long-term survival of patients with solid organ transplantation. Although stem/progenitor cells …

Sustained, indolent immune injury of the vasculature of a heart transplant limits long-term
graft and recipient survival. This injury is mitigated by a poorly characterized, maladaptive …

Donor-specific antibodies (DSA) are integral to the development of antibody-mediated
rejection (AMR). Chronic AMR is associated with high mortality and an increased risk for …

The zinc finger protein ZFYVE21 is involved in immune signaling. Using humanized mouse
models, primary human cells, and patient samples, we identified a T cell–autonomous role …

Restenosis is mainly attributed to excessive proliferation of vascular smooth muscle cells
(VSMCs). Noncoding RNAs have been identified as key regulators of diverse pathological …