Multiscale models of angiogenesis

AA Qutub, F Mac Gabhann… - IEEE engineering in …, 2009 - ieeexplore.ieee.org
This article aims to promote integration of angiogenesis-related models, both integration of
the work described herein and many other existing and future models. Integration of …

Gene transfer: the challenge of regulated gene expression

ZS Guo, Q Li, DL Bartlett, JY Yang, B Fang - Trends in molecular medicine, 2008 - cell.com
Gene therapy is expected to have a major impact on human healthcare in the future.
However, precise regulation of therapeutic gene expression in vivo is still a challenge …

[图书][B] Embryogenesis explained

NK Gordon, R Gordon - 2016 - books.google.com
The greatest mystery of life is how a single fertilized egg develops into a fully functioning,
sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory …

Signaling flux redistribution at toll-like receptor pathway junctions

K Selvarajoo, Y Takada, J Gohda, M Helmy, S Akira… - PLoS …, 2008 - journals.plos.org
Various receptors on cell surface recognize specific extracellular molecules and trigger
signal transduction altering gene expression in the nucleus. Gain or loss-of-function …

[图书][B] OMICS: biomedical perspectives and applications

D Barh, K Blum, MA Madigan - 2016 - books.google.com
A reflection of the explosion of research and development in this field, this book explores
applications of omics in bioinformatics, cancer research and therapy, diabetes research …

Can complex cellular processes be governed by simple linear rules?

K Selvarajoo, M Tomita, M Tsuchiya - Journal of Bioinformatics and …, 2009 - World Scientific
Complex living systems have shown remarkably well-orchestrated, self-organized, robust,
and stable behavior under a wide range of perturbations. However, despite the recent …

Systems biology strategy reveals PKCδ is key for sensitizing TRAIL-resistant human fibrosarcoma

K Hayashi, S Tabata, V Piras, M Tomita… - Frontiers in …, 2015 - frontiersin.org
Cancer cells are highly variable and largely resistant to therapeutic intervention. Recently,
the use of the tumor necrosis factor related apoptosis-inducing ligand (TRAIL) induced …

Robustness under Functional Constraint: The Genetic Network for Temporal Expression in Drosophila Neurogenesis

A Nakajima, T Isshiki, K Kaneko… - PLoS Computational …, 2010 - journals.plos.org
Precise temporal coordination of gene expression is crucial for many developmental
processes. One central question in developmental biology is how such coordinated …

[图书][B] The Future of Scientific Practice:'bio-techno-logos'

M Bertolaso - 2015 - books.google.com
Focusing on cell dynamics, molecular medicine and robotics, contributors explore the
interplay between biological, technological and theoretical ways of thinking. The collection …

Genomic-Thermodynamic Phase Synchronization: Maxwell's Demon-Like Regulation of Cell Fate Transition

M Tsuchiya, K Yoshikawa, A Giuliani - bioRxiv, 2024 - biorxiv.org
Dynamic criticality-the balance between order and chaos-is fundamental in genome
regulation and cellular transitions. In this study, we investigate the distinct behaviors of gene …