MicroRNAs (miRNAs) are crucial post-transcriptional regulators of haematopoietic cell fate
decisions. They act by negatively regulating the expression of key immune development …

Early electron microscopy studies revealed the elaborate cellular features that define the
unique adaptations of apicomplexan parasites. Among these were bulbous rhoptry (ROP) …

摘要背景: 1 型糖尿病是一种常见的由自身免疫细胞介导的胰岛β 细胞受损的自身免疫性疾病.
研究表明microRNAs (miRNAs) 的异常表达可导致自身免疫性疾病的发生 …

The aging process is driven by a finite number of inter‐related mechanisms that ultimately
lead to the emergence of characteristic phenotypes, including increased susceptibility to …

The central dogma of molecular biology states that the functions of RNA revolve around
protein translation. Until the last decade, most researches were geared towards …

Tumor necrosis factor receptor (TNFR)‐associated factor 6 (TRAF 6) is an adapter protein
that mediates a wide array of protein–protein interactions via its TRAF domain and a RING …

The innate inflammatory response must be tightly regulated to ensure effective immune
protection. NF-κB is a key mediator of the inflammatory response, and its dysregulation has …

Although T cell help for B cells was described several decades ago, it was the identification
of CXCR5 expression by B follicular helper T (Tfh) cells and the subsequent discovery of …

Activation of inflammatory pathways in the endothelium contributes to vascular diseases,
including sepsis and atherosclerosis. We demonstrate that miR‐146a and miR‐146b are …

MicroRNAs (miRNAs or miRs) are a class of evolutionarily-conserved small, regulatory non-
coding RNAs, 19–3 nucleotides in length, that negatively regulate protein coding gene …