Anti-inflammatory effect of muscle-derived interleukin-6 and its involvement in lipid metabolism

H Nara, R Watanabe - International journal of molecular sciences, 2021 - mdpi.com
Interleukin (IL)-6 has been studied since its discovery for its role in health and diseases. It is
one of the most important pro-inflammatory cytokines. IL-6 was reported as an exacerbating …

Aerobic exercise training and gut microbiome-associated metabolic shifts in women with overweight: a multi-omic study

JE Hintikka, JP Ahtiainen, P Permi, S Jalkanen… - Scientific Reports, 2023 - nature.com
Physical activity is essential in weight management, improves overall health, and mitigates
obesity-related risk markers. Besides inducing changes in systemic metabolism, habitual …

Myoblast‐derived exosomes promote the repair and regeneration of injured skeletal muscle in mice

S Ji, P Ma, X Cao, J Wang, X Yu, X Luo, J Lu… - FEBS Open …, 2022 - Wiley Online Library
When skeletal muscle is damaged, satellite cells (SCs) are activated to proliferate rapidly
and fuse with the damaged muscle fibers to form new muscle fibers, thereby promoting …

Blueberry and/or banana consumption mitigate arachidonic, cytochrome P450 oxylipin generation during recovery from 75-km cycling: a randomized trial

DC Nieman, ND Gillitt, GY Chen, Q Zhang, W Sha… - Frontiers in …, 2020 - frontiersin.org
Oxylipins are bioactive lipid oxidation products, have vital regulatory roles in numerous
physiological processes including inflammation, and can be impacted by diet. This study …

Porcine cytochrome 2A19 and 2E1

V Burkina, MK Rasmussen… - Basic & Clinical …, 2019 - Wiley Online Library
Cytochrome P450 (CYP) is a major group of enzymes, which conduct Phase I metabolism.
Among commonly used animal models, the pig has been suggested as the most suitable …

Interleukin-6 mediated exercise-induced alleviation of adiposity and hepatic steatosis in mice

L Li, C Huang, H Yin, X Zhang, D Wang, C Ma… - BMJ Open Diabetes …, 2021 - drc.bmj.com
Introduction Exercise training has been shown to be the most effective strategy to combat
obesity and non-alcoholic fatty liver disease. However, exercise promotes loss of adipose …

Background diet influences TMAO concentrations associated with red meat intake without influencing apparent hepatic TMAO-related activity in a porcine model

R Thøgersen, MK Rasmussen, UK Sundekilde… - Metabolites, 2020 - mdpi.com
Red meat has been associated with an increased cardiovascular disease (CVD) risk,
possibly through gut microbial-derived trimethylamine-N-oxide (TMAO). However, previous …

Effects of Crocodile Oil (Crocodylus siamensis) on Liver Enzymes: Cytochrome P450 and Glutathione S‐Transferase Activities in High‐fat DietFed Rats

P Santativongchai, K Srisuksai… - Veterinary medicine …, 2022 - Wiley Online Library
Crocodile oil is a highly effective treatment for ailments ranging from skin conditions to
cancer. However, the effects of the oil on liver detoxification pathways are not well studied …

[HTML][HTML] Hepatic PGC-1α has minor regulatory effect on the liver transcriptome and metabolome during high fat high fructose diet and exercise training

MK Rasmussen, R Thøgersen, PH Lindholm… - Gene, 2023 - Elsevier
The prevalence of non-alcoholic fatty liver diseases (NAFLD) has reached epidemic levels
during recent years and a major driver of NAFLD are diets high in fat and fructose. A …

Exercise Affects the Formation and Recovery of Alcoholic Liver Disease through the IL-6–p47phox Oxidative–Stress Axis

W Cui, X Li, W Xue, H Wei, G Zhou, Y Qiu, D Cui - Cells, 2022 - mdpi.com
(1) Background: To explore the effect of exercise on the formation and recovery of alcoholic
liver disease (ALD) and whether the IL-6–p47phox oxidative–stress axis is involved in that …