Complement is activated during malaria infection, but there is little evidence that it benefits
the host. On the contrary, growing evidence points to the central role of complement …

Malaria is widely reported to suppress immune responses to heterologous antigens,
including vaccines, but the evidence base for this assumption is patchy and confusing. Here …

Background Malaria remains a major public health problem in Indonesian Papua, with
children under five years of age being the most affected group. Haematological changes …

Background Falciparum Malaria, an infectious disease caused by the apicomplexan
parasite Plasmodium falciparum, is among the leading causes of death and morbidity …

Sequestration of parasitized erythrocytes and dysregulation of the coagulation and
complement system are hallmarks of severe Plasmodium falciparum malaria. A link between …

Abstract Objective Anemia, Leukopenia, and thrombocytopenia are commonly observed
hematological abnormalities in malaria and typhoid patients. In this study, we evaluated the …

Severe Plasmodium falciparum malaria evolves through the interplay among capillary
sequestration of parasitized erythrocytes, deregulated inflammatory responses, and …

Anemia is a major complication of malaria, driven largely by loss of uninfected RBCs during
infection. RBC clearance through loss of complement regulatory proteins (CRPs) is a …

The digestive vacuole (DV) of Plasmodium falciparum, which is released into the
bloodstream upon rupture of each parasitized red blood cell (RBC), was recently discovered …

Background. Coinfections are becoming common risk factors that may contribute to the
increased burden of morbidity in pregnancy. The aim of this study was to assess the …