[HTML][HTML] Exploration of the therapeutic aspects of Lck: A kinase target in inflammatory mediated pathological conditions

PK Singh, A Kashyap, O Silakari - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Lck, a non-receptor src family kinase, plays a vital role in various cellular processes such as
cell cycle control, cell adhesion, motility, proliferation and differentiation. As a 56 KDa …

Idiopathic CD4 lymphocytopenia: current insights

S Vijayakumar, S Viswanathan… - ImmunoTargets and …, 2020 - Taylor & Francis
Idiopathic CD4 lymphocytopenia is a condition characterized by low CD4 counts. It is rare
and most of the information about this illness comes from case reports. Presentation is …

Idiopathic CD4 lymphocytopenia: Pathogenesis, etiologies, clinical presentations and treatment strategies

H Yarmohammadi, C Cunningham-Rundles - Annals of Allergy, Asthma & …, 2017 - Elsevier
Abstract Background Idiopathic CD4 lymphocytopenia (ICL) is a rare condition characterized
by an unexplained deficit of circulating CD4 T cells leading to increased risk of serious …

[PDF][PDF] Pathology of HIV/AIDS

EC Klatt - The Mercer University of Medicine Savannah, 2017 - webpath.med.utah.edu
The human immunodeficiency virus (HIV) was unknown until the early 1980's when
increasing numbers of cases of unusual opportunistic infections and Kaposi sarcoma in …

Characterization of infants with idiopathic transient and persistent T cell lymphopenia identified by newborn screening—a single-center experience in New York state

AM Jongco, R Sporter, E Hon, O Elshaigi… - Journal of Clinical …, 2021 - Springer
Purpose Newborn screening (NBS) quantifies T cell receptor excision circles (TREC) and
identifies infants with T cell lymphopenia (TCL). This study elucidates the demographics …

Idiopathic CD4 lymphocytopenia.

JP Brooks, G Ghaffari - Allergy & Asthma Proceedings, 2016 - search.ebscohost.com
Abstract Background: Idiopathic CD4 lymphocytopenia (ICL) is a rare disorder of unknown
etiology. Diagnostic criteria include a persistent CD4 T-cell lymphopenia with no underlying …

Identification of important modules and biomarkers that are related to immune infiltration cells in severe burns based on weighted gene co-expression network …

Z Zhang, Y He, R Lin, J Lan, Y Fan, P Wang… - Frontiers in …, 2022 - frontiersin.org
Background: Immunosuppression is an important trigger for infection and a significant cause
of death in patients with severe burns. Nevertheless, the prognostic value of immune-related …

Disseminated cryptococcosis with varicella-zoster virus coinfection of idiopathic CD4+ T lymphocytopenia: a case report and literature review

L Fang, J Zhang, F Lv - Virology Journal, 2022 - Springer
Abstract Background Idiopathic CD4+ T lymphocytopenia (ICL) is a rare immunodeficiency
syndrome, unaccompanied by various opportunistic infections. Cryptococcus and varicella …

[HTML][HTML] Severe disseminated Talaromyces marneffei infection in Idiopathic CD4 Lymphopenia

B Li, T Li, Q Lu, D Liang, C Cao - IDCases, 2025 - Elsevier
Idiopathic CD4 lymphopenia (ICL) is a rare non–HIV-related syndrome, characterized by a
reduced CD4 T-cell count and a predisposition to various opportunistic infections. However …

Immunodeficiencies affecting cellular and humoral immunity

Z Chavoshzadeh, S Darougar, T Momen… - Inborn errors of …, 2021 - Elsevier
Combined immunodeficiencies (CIDs) are the result of defective development or function of
T cells. As the most severe form of primary immunodeficiency disorders (PID), CIDs are …