CFIm-mediated alternative polyadenylation remodels cellular signaling and miRNA biogenesis
The mammalian cleavage factor I (CFIm) has been implicated in alternative polyadenylation
(APA) in a broad range of contexts, from cancers to learning deficits and parasite infections …
(APA) in a broad range of contexts, from cancers to learning deficits and parasite infections …
Shortening of 3′ UTRs in most cell types composing tumor tissues implicates alternative polyadenylation in protein metabolism
D Burri, M Zavolan - RNA, 2021 - rnajournal.cshlp.org
During pre-mRNA maturation 3′ end processing can occur at different polyadenylation
sites in the 3′ untranslated region (3′ UTR) to give rise to transcript isoforms that differ in …
sites in the 3′ untranslated region (3′ UTR) to give rise to transcript isoforms that differ in …