The immune system is a complex set of physiological mechanisms whose general aim is to
defend the organism against non-self-bodies, such as pathogens (bacteria, viruses …

Circadian rhythms occur in almost all species and control vital aspects of our physiology,
from sleeping and waking to neurotransmitter secretion and cellular metabolism …

The enteric nervous system (ENS) coordinates diverse functions in the intestine but has
eluded comprehensive molecular characterization because of the rarity and diversity of …

Mammalian circadian behaviors are orchestrated by the suprachiasmatic nucleus (SCN) in
the ventral hypothalamus, but the number of SCN cell types and their functional roles remain …

In mammals, endogenous circadian clocks sense and respond to daily feeding and lighting
cues, adjusting internal∼ 24 h rhythms to resonate with, and anticipate, external cycles of …

A cardinal symptom of major depressive disorder (MDD) is the disruption of circadian
patterns. However, to date, there is no direct evidence of circadian clock dysregulation in the …

Insufficient sleep and circadian rhythm disruption are associated with negative health
outcomes, including obesity, cardiovascular disease, and cognitive impairment, but the …

The suprachiasmatic nucleus (SCN) is the primary circadian pacemaker in mammals.
Individual SCN neurons in dispersed culture can generate independent circadian …

Circadian rhythms control metabolism and energy homeostasis, but the role of the skeletal
muscle clock has never been explored. We generated conditional and inducible mouse …

Background Co-expression measures are often used to define networks among genes.
Mutual information (MI) is often used as a generalized correlation measure. It is not clear …