The artificial pancreas (AP), known as closed-loop control of blood glucose in diabetes, is a
system combining a glucose sensor, a control algorithm, and an insulin infusion device. AP …

The control of diabetes is an interdisciplinary endeavor, which includes a significant
biomedical engineering component, with traditions of success beginning in the early 1960s …

Background: A new version of the UVA/Padova Type 1 Diabetes (T1D) Simulator is
presented which provides a more realistic testing scenario. The upgrades to the previous …

Integrated closed-loop control (CLC), combining continuous glucose monitoring (CGM) with
insulin pump (continuous subcutaneous insulin infusion [CSII]), known as artificial pancreas …

Modularity plays a key role in many engineering systems, allowing for plug-and-play
integration of components, enhancing flexibility and adaptability, and facilitating …

Safe and widespread use of diabetes technology is constrained by alarm fatigue: When
someone receives so many alarms that he or she becomes less likely to respond …

One of the difficulties in the development of a reliable artificial pancreas for people with type
1 diabetes mellitus (T1DM) is the lack of accurate models of an individual's response to …

Objective: Contemporary and future outpatient long-term artificial pancreas (AP) studies
need to cope with the well-known large intra-and interday glucose variability occurring in …

Blood glucose control, for example, in diabetes mellitus or severe illness, requires strict
adherence to a protocol of food, insulin administration and exercise personalized to each …

Current methods of drug dosing rely on physical parameters (such as sex, age and weight)
that do not account for genetic and physiological differences among individual patients …