Preventative options and the future of chemoprevention for cutaneous tumors

JM Anderson, L Moy, RL Moy - Dermatologic Clinics, 2023 - derm.theclinics.com
Chemoprophylaxis is defined as the use of drugs, vitamins, or other agents to prevent
against or to slow the development of cancer. Treatment of nonmelanoma skin cancer …

Metformin is associated with decreased risk of basal cell carcinoma: A whole-population case-control study from Iceland

JA Adalsteinsson, S Muzumdar, R Waldman… - Journal of the American …, 2021 - Elsevier
Background Metformin has anticarcinogenic properties and is also known to inhibit the sonic
hedgehog pathway, but population-based studies analyzing the potential protective effect for …

Risk of skin cancer associated with metformin use: A meta-analysis of randomized controlled trials and observational studies

MS Chang, RI Hartman, J Xue, EL Giovannucci… - Cancer Prevention …, 2021 - AACR
Previous studies demonstrate mixed evidence regarding the association between metformin
and skin cancer risk. To synthesize prior evidence and evaluate the association between …

Association between prescribed oral antidiabetic medication for type 2 diabetes mellitus and risk of skin cancer: a systematic review and meta-analysis

C Simpson, S Leducq, Z Venables… - British Journal of …, 2025 - academic.oup.com
We conducted a systematic review to determine if there is a significant association between
prescribed oral antidiabetic medication and the risk of developing skin cancer [basal cell …

Oral intake of bucillamine, carvedilol, metformin, or phenformin does not protect against UVR-induced squamous cell carcinomas in hairless mice

C Pihl, P Bjerring, F Andersen, M Haedersdal… - Photochemical & …, 2024 - Springer
Squamous cell carcinoma represents the second most common type of keratinocyte
carcinoma with ultraviolet radiation (UVR) making up the primary risk factor. Oral …

Metformin in skin diseases

D Kadylak, K Polak, K Wojciechowska… - Dermatology Review …, 2021 - termedia.pl
Metformin is the most widely used oral antidiabetic drug in the world. It is the first-line drug in
type 2 diabetes, where its inhibiting effect on hepatic glucose production, increasing muscle …