On peptides and altered peptide ligands: from origin, mode of action and design to clinical application (immunotherapy)
M Candia, B Kratzer, WF Pickl - International archives of allergy and …, 2016 - karger.com
T lymphocytes equipped with clonotypic T cell antigen receptors (TCR) recognize
immunogenic peptides only when presented in the context of their own major …
immunogenic peptides only when presented in the context of their own major …
Mechanistic understanding and significance of small peptides interaction with MHC class II molecules for therapeutic applications
S Afridi, DC Hoessli, MW Hameed - Immunological Reviews, 2016 - Wiley Online Library
Major histocompatibility complex (MHC) class II molecules are expressed by antigen‐
presenting cells and stimulate CD 4+ T cells, which initiate humoral immune responses …
presenting cells and stimulate CD 4+ T cells, which initiate humoral immune responses …
Spectroscopic characterization of eupalitin-3-O-β-D-galactopyranoside from Boerhavia procumbens: In vivo hepato-protective potential in rat model
The liver is one of the most important organs responsible for detoxifying biomolecules and
xenobiotics. Herein, we report the isolation, characterization, and hepatoprotective effect of …
xenobiotics. Herein, we report the isolation, characterization, and hepatoprotective effect of …
Total synthesis, structural, and biological evaluation of stylissatin A and related analogs
F Shaheen, A Jabeen, S Ashraf… - Journal of Peptide …, 2016 - Wiley Online Library
The natural product cyclic peptide stylissatin A (1a) was reported to inhibit nitric oxide
production in LPS‐stimulated murine macrophage RAW 264.7 cells. In the current study …
production in LPS‐stimulated murine macrophage RAW 264.7 cells. In the current study …
Small organic molecules accelerate the expansion of regulatory T cells
The regulatory T cells (T reg cells) expressing CD4+ CD25+ FOXP3+ markers are
indispensable for the initiation of immune homeostasis and tolerance to self-antigens in both …
indispensable for the initiation of immune homeostasis and tolerance to self-antigens in both …