Defining and assessing animal pain

LU Sneddon, RW Elwood, SA Adamo, MC Leach - Animal behaviour, 2014 - Elsevier
Highlights•Assessing pain in animals is problematic without a distinct definition.•We provide
clear criteria for animal pain that can be used to evaluate if pain occurs.•The empirical …

[HTML][HTML] Do the right thing: neural network mechanisms of memory formation, expression and update in Drosophila

P Cognigni, J Felsenberg, S Waddell - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Recurrent connectivity is anatomically and functionally prevalent in fly memory
circuits.•Sustained reverberant activity is necessary for memory consolidation.•Feedforward …

The connectome of an insect brain

M Winding, BD Pedigo, CL Barnes, HG Patsolic, Y Park… - Science, 2023 - science.org
Brains contain networks of interconnected neurons and so knowing the network architecture
is essential for understanding brain function. We therefore mapped the synaptic-resolution …

The complete connectome of a learning and memory centre in an insect brain

K Eichler, F Li, A Litwin-Kumar, Y Park, I Andrade… - Nature, 2017 - nature.com
Associating stimuli with positive or negative reinforcement is essential for survival, but a
complete wiring diagram of a higher-order circuit supporting associative memory has not …

Dopamine neurons projecting to the posterior striatum reinforce avoidance of threatening stimuli

W Menegas, K Akiti, R Amo, N Uchida… - Nature …, 2018 - nature.com
Midbrain dopamine neurons are well known for their role in reward-based reinforcement
learning. We found that the activity of dopamine axons in the posterior tail of the striatum …

The neuronal architecture of the mushroom body provides a logic for associative learning

Y Aso, D Hattori, Y Yu, RM Johnston, NA Iyer, TTB Ngo… - elife, 2014 - elifesciences.org
We identified the neurons comprising the Drosophila mushroom body (MB), an associative
center in invertebrate brains, and provide a comprehensive map describing their potential …

A connectome of a learning and memory center in the adult Drosophila brain

S Takemura, Y Aso, T Hige, A Wong, Z Lu, CS Xu… - Elife, 2017 - elifesciences.org
Understanding memory formation, storage and retrieval requires knowledge of the
underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of …

[HTML][HTML] Coordinated and compartmentalized neuromodulation shapes sensory processing in Drosophila

R Cohn, I Morantte, V Ruta - Cell, 2015 - cell.com
Learned and adaptive behaviors rely on neural circuits that flexibly couple the same sensory
input to alternative output pathways. Here, we show that the Drosophila mushroom body …

Context-dependent representations of movement in Drosophila dopaminergic reinforcement pathways

A Zolin, R Cohn, R Pang, AF Siliciano, AL Fairhall… - Nature …, 2021 - nature.com
Dopamine plays a central role in motivating and modifying behavior, serving to invigorate
current behavioral performance and guide future actions through learning. Here we examine …

[图书][B] The ancient origins of consciousness: How the brain created experience

TE Feinberg, JM Mallatt - 2016 - books.google.com
How consciousness appeared much earlier in evolutionary history than is commonly
assumed, and why all vertebrates and perhaps even some invertebrates are conscious …