Emerging strategies for combating Fusobacterium nucleatum in colorectal cancer treatment: Systematic review, improvements and future challenges

H Liu, Y Yu, A Dong, M Elsabahy, YW Yang… - Exploration, 2024 - Wiley Online Library
Colorectal cancer (CRC) is generally characterized by a high prevalence of Fusobacterium
nucleatum (F. nucleatum), a spindle‐shaped, Gram‐negative anaerobe pathogen derived …

Berberine a traditional Chinese drug repurposing: Its actions in inflammation-associated ulcerative colitis and cancer therapy

C Zhu, K Li, XX Peng, TJ Yao, ZY Wang, P Hu… - Frontiers in …, 2022 - frontiersin.org
Berberine (BBR), an isoquinoline alkaloid extracted from Coptidis Rhizoma, has a long
history of treating dysentery in the clinic. Over the past two decades, the polytrophic …

Infection and the microbiome in bronchiectasis

M Mac Aogáin, AJ Dicker, P Mertsch… - European …, 2024 - publications.ersnet.org
Bronchiectasis is marked by bronchial dilatation, recurrent infections and significant
morbidity, underpinned by a complex interplay between microbial dysbiosis and immune …

[HTML][HTML] A trait-based ecological perspective on the soil microbial antibiotic-related genetic machinery

O Dulya, V Mikryukov, DV Shchepkin, M Pent… - Environment …, 2024 - Elsevier
Antibiotic resistance crisis dictates the need for resistance monitoring and the search for new
antibiotics. The development of monitoring protocols is hindered by the great diversity of …

[HTML][HTML] Compartmentalization of the host microbiome: how tumor microbiota shapes checkpoint immunotherapy outcome and offers therapeutic prospects

M Boesch, L Horvath, F Baty, A Pircher… - … for immunotherapy of …, 2022 - ncbi.nlm.nih.gov
The host microbiome is polymorphic, compartmentalized, and composed of distinctive tissue
microbiomes. While research in the field of cancer immunotherapy has provided an …

Advances in the gut microbiome and mood disorders

S Mörkl, MI Butler, S Lackner - Current Opinion in Psychiatry, 2023 - journals.lww.com
Gut microbiome modulations allow new treatment strategies including the use of
psychobiotics for the treatment and prevention of mood disorders. Well designed clinical …

Targeting respiratory microbiomes in COPD and bronchiectasis

M Mac Aogáin, PY Tiew, TK Jaggi… - Expert Review of …, 2024 - Taylor & Francis
Introduction This review summarizes our current understanding of the respiratory
microbiome in COPD and Bronchiectasis. We explore the interplay between microbial …

Targeting microbiome, drug metabolism, and drug delivery in oncology

A Sumiyoshi, H Fujii, Y Okuma - Advanced Drug Delivery Reviews, 2023 - Elsevier
Recent emerging scientific evidence shows a relationship between gut microbiota (GM) and
immunomodulation. In the recently published “Hallmarks of Cancer”, the microbiome has …

Precise microbiome engineering using natural and synthetic bacteriophages targeting an artificial bacterial consortium

T Tanaka, R Sugiyama, Y Sato, M Kawaguchi… - Frontiers in …, 2024 - frontiersin.org
In natural microbiomes, microorganisms interact with each other and exhibit diverse
functions. Microbiome engineering, which enables bacterial knockdown, is a promising …

Heterologously expressed SacP23, a novel bacteriocin from Paenibacillus polymyxa #23, is active against methicillin resistant Staphylococcus aureus

CM Khánh, D Van Quyen… - Royal Society Open …, 2023 - royalsocietypublishing.org
Antimicrobial peptides have the potential to be used in a range of applications, including as
an alternative to conventional antibiotics for the treatment of bacterial infections of humans …