The development and functions of multiciliated epithelia

N Spassky, A Meunier - Nature reviews Molecular cell biology, 2017 - nature.com
Multiciliated cells are epithelial cells that are in contact with bodily fluids and are required for
the proper function of major organs including the brain, the respiratory system and the …

Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow–Robin perivascular spaces

RJ Reiter, DX Tan, SJ Kim, MHC Cruz - Brain Structure and Function, 2014 - Springer
Historically, the direct release of pineal melatonin into the capillary bed within the gland has
been accepted as the primary route of secretion. Herein, we propose that the major route of …

Glymphatic solute transport does not require bulk flow

M Asgari, D De Zélicourt, V Kurtcuoglu - Scientific reports, 2016 - nature.com
Observations of fast transport of fluorescent tracers in mouse brains have led to the
hypothesis of bulk water flow directed from arterial to venous paravascular spaces (PVS) …

Irrigant flow within a prepared root canal using various flow rates: a computational fluid dynamics study

C Boutsioukis, T Lambrianidis… - International …, 2009 - Wiley Online Library
Aim To study using computer simulation the effect of irrigant flow rate on the flow pattern
within a prepared root canal, during final irrigation with a syringe and needle. Methodology …

Cerebrospinal fluid mechanics and its coupling to cerebrovascular dynamics

AA Linninger, K Tangen, CY Hsu… - Annual Review of Fluid …, 2016 - annualreviews.org
Cerebrospinal fluid (CSF) is not stagnant but displays fascinating oscillatory flow patterns
inside the ventricular system and reversing fluid exchange between the cranial vault and …

Boundary conditions investigation to improve computer simulation of cerebrospinal fluid dynamics in hydrocephalus patients

S Gholampour, N Fatouraee - Communications biology, 2021 - nature.com
Three-D head geometrical models of eight healthy subjects and 11 hydrocephalus patients
were built using their CINE phase-contrast MRI data and used for computer simulations …

Mathematical models of blast-induced TBI: current status, challenges, and prospects

RK Gupta, A Przekwas - Frontiers in neurology, 2013 - frontiersin.org
Blast-induced traumatic brain injury (TBI) has become a signature wound of recent military
activities and is the leading cause of death and long-term disability among US soldiers. The …

Dispersion in porous media in oscillatory flow between flat plates: applications to intrathecal, periarterial and paraarterial solute transport in the central nervous system

M Keith Sharp, RO Carare, BA Martin - Fluids and Barriers of the CNS, 2019 - Springer
Background As an alternative to advection, solute transport by shear-augmented dispersion
within oscillatory cerebrospinal fluid flow was investigated in small channels representing …

CNS wide simulation of flow resistance and drug transport due to spinal microanatomy

KM Tangen, Y Hsu, DC Zhu, AA Linninger - Journal of biomechanics, 2015 - Elsevier
Spinal microstructures are known to substantially affect cerebrospinal fluid patterns, yet their
actual impact on flow resistance has not been quantified. Because the length scale of …

Tanycytes: A rich morphological history to underpin future molecular and physiological investigations

E Rodríguez, M Guerra, B Peruzzo… - Journal of …, 2019 - Wiley Online Library
Tanycytes are located at the base of the brain and retain characteristics from their
developmental origins, such as radial glial cells, throughout their life span. With transport …