Introduction: Respiratory drug delivery is a surprisingly complex process with a number of
physical and biological challenges. Computational fluid dynamics (CFD) is a scientific …

Effective evaluation and prediction of aerosol transport deposition in the human respiratory
tracts are critical to aerosol drug delivery and evaluation of inhalation products …

Regulatory science for generic dry powder inhalers (DPIs) in the United States (US) has
evolved over the last decade. In 2013, the US Food and Drug Administration (FDA) …

Smoke bombs are often used in military/fire training, which can produce a large amount of
zinc chloride (ZnCl2) smoke. Inhalation of ZnCl2 smoke usually causes acute lung injury …

While dry powder aerosol formulations offer a number of advantages, their use in children is
often limited due to poor lung delivery efficiency and difficulties with consistent dry powder …

There have been significant advancements in the various imaging techniques being used
for the evaluation of asthmatic patients, both from a clinical and research perspective …

In silico mechanistic modeling approaches have been designed by various stakeholders
with the goal of supporting development and approval of generic orally inhaled drug …

The development of a CFD model, from initial geometry to experimentally validated results
with engineering insight, can be a time-consuming process that often requires several …

Background: Computational fluid dynamics (CFD) provides a powerful tool for developing
new high-efficiency aerosol delivery strategies, such as nose-to-lung (N2L) aerosol …

Bacterial pneumonia is a serious disease with high mortality if no appropriate and
immediate therapy is available. Andrographolide (AG) is an anti-inflammatory agent …