Biomarkers play a vital role in disease detection and treatment follow-up. It is important to
note that diseases in the early stage are typically treated with the greatest probability of …

Prostate cancer (PC) is one of the most common tumors and a leading cause of mortality
among men, resulting in~ 375 000 deaths annually worldwide. Various analytical methods …

During the years investigators have searched continuously for the ideal tumor marker for
adenocarcinoma of the prostate. For more than a half century acid phosphatase has been …

The human tissue kallikrein gene family was, until recently, thought to consist of only three
genes. Two of these human kallikreins, prostate-specific antigen and human glandular …

Prostate‐specific antigen (PSA) is one of the three most abundant prostatic‐secreted
proteins in human semen. It is a serine proteinase that, in its primary structure, manifests …

A literature review on kinin pharmacology that appeared in this journal in 1980 was based
on a systematic effort to define two receptor types for bradykinin-(BK b) related peptides, and …

The 15 members of the kallikrein-related serine peptidase (KLK) family have diverse tissue-
specific expression profiles and putative proteolytic functions. The kallikrein family is also …

Transcription of the prostate-specific antigen (PSA) gene is androgen regulated. The PSA
promoter contains at position− 170 the sequence AGAACAgcaAGTGCT, which is closely …

Tissue kallikreins are members of the S1 family (clan SA) of trypsin-like serine proteases
and are present in at least six mammalian orders. In humans, tissue kallikreins (hK) are …

Prostate-specific antigen (PSA) is expressed at a high level in the luminal epithelial cells of
the prostate and is absent or expressed at very low levels in other tissues. PSA expression …