A world malaria map: Plasmodium falciparum endemicity in 2007

SI Hay, CA Guerra, PW Gething, AP Patil… - PLoS …, 2009 - journals.plos.org
Background Efficient allocation of resources to intervene against malaria requires a detailed
understanding of the contemporary spatial distribution of malaria risk. It is exactly 40 y since …

Pharmacokinetics and pharmacodynamics of endoperoxide antimalarials

A Gautam, T Ahmed, V Batra… - Current drug …, 2009 - ingentaconnect.com
There are several clinically useful endoperoxides, mainly artemisinin derivatives available in
market for the treatment of malaria. These are highly potent drugs, with fastest parasite …

Recent advances in transmission-blocking drugs for malaria elimination

I Wadi, M Nath, AR Anvikar, P Singh… - Future Medicinal …, 2019 - Taylor & Francis
The scientific community worldwide has realized that malaria elimination will not be possible
without development of safe and effective transmission-blocking interventions. Primaquine …

Therapeutic acetaminophen is not associated with liver injury in children: a systematic review

EJ Lavonas, KM Reynolds, RC Dart - Pediatrics, 2010 - publications.aap.org
BACKGROUND: Concern exists about the potential for liver injury with therapeutic dosing of
acetaminophen in children. OBJECTIVE: We systematically reviewed the medical literature …

Use of Peroxisome Proliferator-Activated Receptor γ Agonists as Adjunctive Treatment for Plasmodium falciparum Malaria: A Randomized, Double-Blind, Placebo …

AK Boggild, S Krudsood, SN Patel… - Clinical Infectious …, 2009 - academic.oup.com
Background. Despite the use of potent antimalarial drugs, the fatality rate associated with
severe malaria remains high. Adjunctive therapies that target the immunopathological …

[HTML][HTML] Liver function test abnormalities in experimental and clinical Plasmodium vivax infection

A Odedra, L Webb, L Marquart, LJ Britton… - The American Journal …, 2020 - ncbi.nlm.nih.gov
Liver transaminase elevations after treatment in malaria volunteer infection studies (VISs)
have raised safety concerns. We investigated transaminase elevations from two human …

Evaluation of antimalarial resistance marker polymorphism in returned migrant workers in China

J Feng, J Li, H Yan, X Feng, Z Xia - Antimicrobial agents and …, 2015 - Am Soc Microbiol
Imported malaria has been a great challenge for public health in China due to decreased
locally transmitted cases and frequent exchange worldwide. Plasmodium falciparum has …

Artemisinin-based combination therapy for uncomplicated malaria in sub-Saharan Africa: the efficacy, safety, resistance and policy implementation since Abuja 2000

A Ogbonna, CJ Uneke - Transactions of the Royal Society of …, 2008 - academic.oup.com
Following increased resistance of malaria parasites to conventional drugs in the malarial
regions of the world, the WHO is promoting artemisinin-based combination therapy (ACT) for …

Prevalence of In Vitro Resistance to Eleven Standard or New Antimalarial Drugs among Plasmodium falciparum Isolates from Pointe-Noire, Republic of the Congo

B Pradines, P Hovette, T Fusai, HL Atanda… - Journal of Clinical …, 2006 - Am Soc Microbiol
We determined the level of in vitro resistance of Plasmodium falciparum parasites to
standard antimalarial drugs, such as chloroquine, quinine, amodiaquine, halofantrine …

High efficacy of two artemisinin‐based combinations (artemether–lumefantrine and artesunate plus amodiaquine) for acute uncomplicated malaria in Ibadan, Nigeria

CO Falade, AO Ogundele, BO Yusuf… - Tropical Medicine & …, 2008 - Wiley Online Library
Objective To test the hypothesis that artesunate plus amodiaquine (ASAQ) is as effective as
artemether–lumefantrine (AL) in the treatment of acute uncomplicated malaria in Nigerian …