The histiocytoses are rare disorders characterized by the accumulation of macrophage,
dendritic cell, or monocyte-derived cells in various tissues and organs of children and adults …

Context Rosai-Dorfman disease is an uncommon histiocytic disorder most frequently
presenting as bilateral cervical lymphadenopathy in children and young adults. Extranodal …

Histiocytoses constitute a heterogeneous group of rare disorders, characterised by
infiltration of almost any organ by myeloid cells with diverse macrophage or dendritic cell …

Patients with autoinflammatory diseases present with noninfectious fever flares and systemic
and/or disease-specific organ inflammation. Their excessive proinflammatory cytokine and …

Histiocytic neoplasms are rare hematologic disorders accounting for less than 1% of cancers
of the soft tissue and lymph nodes. Clinical presentation and prognosis of these disorders …

Nucleoside and nucleobase analogs are currently used in the treatment of solid tumors,
lymphoproliferative diseases, viral infections such as hepatitis and AIDS, and some …

Objectives Autoinflammatory diseases are a family of immune‐mediated, rare diseases,
some of which, exhibit sensorineural hearing loss (SNHL), suggesting potentially similar …

Autoinflammatory diseases are characterized by innate immunity abnormalities. In
autoinflammatory diseases (AID), inflammatory blood biomarkers are elevated during crisis …

Background H Syndrome is an autosomal recessive disorder characterized by cutaneous
hyperpigmentation, hypertrichosis, and induration with numerous systemic manifestations …

Loss-of-function mutations in the lysosomal nucleoside transporter SLC29A3 cause
lysosomal nucleoside storage and histiocytosis: phagocyte accumulation in multiple organs …