Covering period: up to 2019 Water-soluble natural products constitute a relevant group of
secondary metabolites notably known for presenting potent biological activities. Examples …

Apramycin is a structurally unique member of the 2-deoxystreptamine class of
aminoglycoside antibiotics characterized by a monosubstituted 2-deoxystreptamine ring that …

Novel aprosamine derivatives were synthesized for the development of aminoglycoside
antibiotics active against multidrug-resistant Gram-negative bacteria. The synthesis of …

It is well established that the N-nitrosoamide derived from peracetylated derivatives of N-
acetyl neuraminic acid on treatment with a mixture of sodium isopropoxide and …

An overview of the oxidative deamination of N-acetylneuraminic acid derivatives (Neu5Ac)
leading to the formation of ketodeoxynonulosonic acid (KDN), its stereoisomers and …

The design, synthesis and antiribosomal and antibacterial activity of two novel glycosides of
the aminoglycoside antibiotic paromomycin are described. The first carries of 4-amino-4 …

Sialic acids are molecules of importance in the fields of carbohydrate chemistry and
glycoscience, and their diversity make them even more attractive to scientific research …

Aminoglycosides have been widely recognized as critically important antimicrobials for
treatment of multidrug resistant bacteria. As presented in Chapter 1, though effective against …

This brief review discusses some new developments in the functionalized carb
pharmacophore (FCP) concept introduced by us in 2014. While the examples concentrate …

An overview of the oxidative deamination of N-acetylneuraminic acid derivatives (Neu5Ac)
leading to the formation of ketodeoxynonulosonic acid (KDN), its stereoisomers and …