Adjuvants are key factors for the development of future vaccines: lessons from the Finlay adjuvant platform

O Pérez, B Romeu, O Cabrera, E González… - Frontiers in …, 2013 - frontiersin.org
The development of effective vaccines against neglected diseases, especially those
associated with poverty and social deprivation, is urgently needed. Modern vaccine …

Nanocochleates: A potential drug delivery system

M Tilawat, S Bonde - Journal of Molecular Liquids, 2021 - Elsevier
Efficient therapy is a prime concern in any disease. The conventional way of therapy lacks
behind for many issues. These obstacles were successfully diminished with the application …

Mannose derivative and lipid A dually decorated cationic liposomes as an effective cold chain free oral mucosal vaccine adjuvant-delivery system

N Wang, T Wang, M Zhang, R Chen, R Niu… - European Journal of …, 2014 - Elsevier
To develop convenient, effective cold chain-free subunit vaccines, a mannose-PEG-
cholesterol conjugate (MPC) was synthesized as a lectin binding molecule and anchored …

Intranasal immunization with a proteoliposome-derived cochleate containing recombinant gD protein confers protective immunity against genital herpes in mice

J Del Campo, M Lindqvist, M Cuello, M Bäckström… - Vaccine, 2010 - Elsevier
The purpose of this study was to investigate the potential of intranasal (IN) immunization with
Neisseria meningitides B proteoliposome (AFPL1) and AFPL1-derived cochleate (AFCo1) …

Colloidal drug delivery systems: current status and future directions

T Garg, G Rath, A Goyal - Critical Reviews™ in Therapeutic …, 2015 - dl.begellhouse.com
In this paper, we provide an overview an extensive range of colloidal drug delivery systems
with special focus on vesicular and particulates systems that are being used in research or …

Female genital tract immunity: distinct immunological challenges for vaccine development

RK Naz - Journal of reproductive immunology, 2012 - Elsevier
The population explosion and unintended pregnancies, sexually transmitted diseases
including human immunodeficiency virus, and cervical cancer, are major challenges to …

Mannose-modified chitosan microspheres enhance OprF-OprI-mediated protection of mice against Pseudomonas aeruginosa infection via induction of mucosal …

Z Cui, D Han, X Sun, M Zhang, X Feng, C Sun… - Applied microbiology …, 2015 - Springer
Pseudomonas aeruginosa is an opportunistic pathogen that localizes to and colonizes
mucosal tissue. Thus, vaccines that elicit a strong mucosal response against P. aeruginosa …

Optimizing efficacy of mucosal vaccines

A Gebril, M Alsaadi, R Acevedo, AB Mullen… - Expert review of …, 2012 - Taylor & Francis
In general, there are only a few vaccines administered via mucosal routes, as the mucosal
immune system presents numerous hurdles, including diversity in mucosal surface structure …

Using procedure of emulsification–lyophilization to form lipid A-incorporating cochleates as an effective oral mucosal vaccine adjuvant-delivery system (VADS)

N Wang, T Wang, M Zhang, R Chen, Y Deng - International Journal of …, 2014 - Elsevier
Using a procedure of emulsification–lyophilization (PEL), adjuvant lipid A-cochleates (LACs)
were prepared as a carrier for model antigen bovine serum albumin (BSA). With …

Colloidal drug delivery systems in vaccine delivery

S Beg, A Samad, I Nazish, R Sultana… - Current Drug …, 2013 - ingentaconnect.com
Vaccines play a vital role in the field of community medicine to combat against several
diseases of human existence. Vaccines primarily trigger the acquired immune system to …