Wingless ligands, a family of secreted proteins, are critically involved in organ development
and tissue homeostasis by ensuring balanced rates of stem cell proliferation, cell death and …

Mitochondria are important organelles of eukaryotic cells and involved in a variety of cellular
processes including oxidative phosphorylation for generating ATP, apoptosis, steroid …

Mitochondria synthesize select phospholipids but lack the machinery for synthesis of the
most abundant mitochondrial phospholipid, phosphatidylcholine (PC). Although the …

The deposition of intramuscular (IM) and subcutaneous (SC) fat is an important trait
influencing pork quality. Understanding the genetic differences between these two types of …

Simple Summary Alterations in cholesterol level play an important role in cancer
development. Lipid transfer proteins (LTPs) are involved in cholesterol distribution between …

Irisin, an adipokine, regulates differentiation and phenotype in various cell types including
myocytes, adipocytes, and osteoblasts. Circulating irisin concentration increases throughout …

StarD7 facilitates phosphatidylcholine (PC) transfer to mitochondria, and is essential for
mitochondrial homeostasis. However, the molecular mechanism for PC transfer by protein …

Small molecule degraders of small ubiquitin‐related modifier 1 (SUMO1) induce SUMO1
degradation in colon cancer cells and inhibits the cancer cell growth; however, it is unclear …

Resistance to chemotherapeutic agents is the main reason for treatment failure in patients
with cancer. The primary mechanism of multidrug resistance (MDR) is the overexpression of …

The steroidogenic acute regulatory (StAR) protein-related lipid transfer (START) domain
proteins constitute a family of evolutionarily conserved and widely expressed proteins that …