Fxr signaling and microbial metabolism of bile salts in the zebrafish intestine
J Wen, GP Mercado, A Volland, HL Doden… - Science …, 2021 - science.org
Bile salt synthesis, secretion into the intestinal lumen, and resorption in the ileum occur in all
vertebrate classes. In mammals, bile salt composition is determined by host and microbial …
vertebrate classes. In mammals, bile salt composition is determined by host and microbial …
A nanocomposite consisting of graphene oxide, zeolite imidazolate framework 8, and a molecularly imprinted polymer for (multiple) fiber solid phase microextraction of …
R Mirzajani, F Kardani, Z Ramezani - Microchimica Acta, 2019 - Springer
A method is described for multiple monolithic fiber solid-phase microextraction of five sterol
and steroid hormones from complex food samples. A composite was prepared from …
and steroid hormones from complex food samples. A composite was prepared from …
Development of a multi-class steroid hormone screening method using Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
ASP Boggs, JA Bowden, TM Galligan… - Analytical and …, 2016 - Springer
Monitoring complex endocrine pathways is often limited by indirect measurement or
measurement of a single hormone class per analysis. There is a burgeoning need to …
measurement of a single hormone class per analysis. There is a burgeoning need to …
Tebuconazole disrupts steroidogenesis in Xenopus laevis
A 27-day controlled exposure study of adult male African clawed frogs (Xenopus laevis) was
conducted to examine the mechanism by which tebuconazole may disrupt steroidogenesis …
conducted to examine the mechanism by which tebuconazole may disrupt steroidogenesis …
Multiplexed steroid profiling of gluco-and mineralocorticoids pathways using a liquid chromatography tandem mass spectrometry method
S Travers, L Martinerie, C Bouvattier, P Boileau… - The Journal of steroid …, 2017 - Elsevier
Serum steroid assays are major tools in the clinical evaluation of adrenal disorders. The
main adrenal steroids are routinely measured with immunoassays. However …
main adrenal steroids are routinely measured with immunoassays. However …
High-throughput screening of chemical effects on steroidogenesis using H295R human adrenocortical carcinoma cells
AL Karmaus, CM Toole, DL Filer, KC Lewis… - Toxicological …, 2016 - academic.oup.com
Disruption of steroidogenesis by environmental chemicals can result in altered hormone
levels causing adverse reproductive and developmental effects. A high-throughput assay …
levels causing adverse reproductive and developmental effects. A high-throughput assay …
High-throughput H295R steroidogenesis assay: utility as an alternative and a statistical approach to characterize effects on steroidogenesis
Abstract The US Environmental Protection Agency Endocrine Disruptor Screening Program
and the Organization for Economic Co-operation and Development (OECD) have used the …
and the Organization for Economic Co-operation and Development (OECD) have used the …
Two simple cleanup methods combined with LC-MS/MS for quantification of steroid hormones in in vivo and in vitro assays
JJ Weisser, CH Hansen, R Poulsen, LW Larsen… - Analytical and …, 2016 - Springer
Measuring both progestagens, androgens, corticosteroids as well as estrogens with a single
method makes it possible to investigate the effects of endocrine-disrupting chemicals …
method makes it possible to investigate the effects of endocrine-disrupting chemicals …
LC-MS/MS based profiling and dynamic modelling of the steroidogenesis pathway in adrenocarcinoma H295R cells
KEM Ahmed, HG Frøysa, OA Karlsen, JV Sagen… - Toxicology in Vitro, 2018 - Elsevier
Endocrine disrupting chemicals have been reported to exert effects directly on enzymes
involved in steroid biosynthesis. Here, we present a new liquid chromatography-tandem …
involved in steroid biosynthesis. Here, we present a new liquid chromatography-tandem …
Steroidomic footprinting based on ultra-high performance liquid chromatography coupled with qualitative and quantitative high-resolution mass spectrometry for the …
D Tonoli, C Fürstenberger, J Boccard… - Chemical research in …, 2015 - ACS Publications
The screening of endocrine disrupting chemicals (EDCs) that may alter steroidogenesis
represents a highly important field mainly due to the numerous pathologies, such as cancer …
represents a highly important field mainly due to the numerous pathologies, such as cancer …